Resident Evil 5 Two Player

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Chris is first introduced in Resident Evil as a pointman for the Raccoon City Police Department's S.T.A.R.S. Alpha Team. In the fight against Bio-Organic Weapons (B.O.W), Chris becomes a co-founder of the B.S.A.A, a counter terrorism organization dedicated to fighting the threat of B.O.W's unleashed by criminal or terrorist elements on a global scale.

Jill is first introduced in Resident Evil as a member of the Raccoon Police departments's S.T.A.R.S. Alpha Team. Jill is a co-founder of the B.S.A.A, a counter terrorism organization dedicated to fighting the threat of Bio-Organic Weapons (B.O.W) unleashed by criminal or terrorist elements on a global scale.

Albert Wesker is first introduced in Resident Evil as a triple agent who poses as the leader of S.T.A.R.S. team, and in subsequent sequels as a high-ranking Umbrella scientist who undermines the pharmaceutical organization on behalf of a rival company with the goal of global saturation.

Rebecca Chambers is first introduced in Resident Evil as a supporting character and field medic of the S.T.A.R.S team. Rebecca also appears as the co-protagonist of Resident Evil Zero along with Billy Coen.

Leon Kennedy is first introduced in Resident Evil 2 as a rookie police officer in the Raccoon City Police Department (R.P.D) who escapes from Raccoon City following a zombie outbreak. He is revealed in Resident Evil 4 to have been recruited by the US federal government and trained to become an elite agent who reports directly to the president of the United States.

Claire is first introduced in Resident Evil 2 as a college student looking for her older brother Chris Redfield. She is depicted in subsequent sequels as a worker for a human rights organization called TerraSave, which provides relief and aid to victims of bioterrorism.

Ada Wong is first introduced in Resident Evil 2 as a corporate spy and mercenary. Her clientele has included Albert Wesker and a mysterious organization known only as the "Agency". Ada is occasionally featured as the main character of select scenarios or campaigns in the franchise's video games.

Billy Coen (ビリーコーエン, Birī Kōen) is the co-protagonist of Resident Evil Zero along with Rebecca Chambers.[3][4] He is first mentioned in a police report filed by Chambers that can be found in the Nintendo 64 version of Resident Evil 2, foreshadowing the events of the prequel. A former Second Lieutenant in the United States Marine Corps Force Reconnaissance, Billy is sentenced to death by a military court for massacring 23 people[5] in murky circumstances during a mission in Africa. Billy's flashbacks imply he is innocent and the victim of a cover-up.[6][7] He escapes en route to his execution and seeks refuge in the Ecliptic Express, a stranded train, where he meets Rebecca Chambers. The two form an alliance in order to survive, using their talents to discover the Umbrella Corporation's secrets.[8] Both characters are monitored by the Queen Leech-James Marcus hybrid, who sends various creatures to subdue them. After revealing the details of his demise, the hybrid Marcus fully mutates into the Queen Leech.[8] In the final battle sequence, Billy and Rebecca destroy the Queen Leech by exploiting its vulnerability to sunlight. Rebecca allows Billy to escape, believing his claims that he is innocent and telling the authorities that he subsequently perished in the Arklay Mountains after their encounter. Billy also appears in The Umbrella Chronicles.[8][9]

The main character of Resident Evil 7: Biohazard and Resident Evil Village, Ethan is introduced as a civilian who travels to the Bakers' dilapidated family estate in Dulvey, Louisiana in search of his missing wife Mia, and is later relocated to an undisclosed location in Eastern Europe following the events of Resident Evil 7.

Rosemary "Rose" Winters is the daughter of Ethan Winters and his wife Mia. In Resident Evil Village, she is kidnapped by Mother Miranda, who intends to use her latent powers inherited from her parents to resurrect her own daughter, Eva. After Chris Redfield rescued the real Mia, whom Miranda kidnapped and impersonated, Rosemary is revealed to be a half-Mold through her father's exact nature as a sentient Mold. With the help of Chris, Ethan rescues Rosemary from Miranda but at the cost of his own life.[12]

Rose also serves as the playable character in Village's DLC chapter Shadows of Rose, set sixteen years after the main events of the game.[2] Files reveal that Rose grew up an outcast due to her nature and abilities that manifested throughout her childhood. Rose has also grown distant from her mother and trained by Chris, even being scouted for Hound Wolf Squad. After learning that she can remove her powers, she enters the realm of the Megamycete to recover a crystal capable of doing so. Navigating the realm, she faces both its twisted creations and remnants of those connected to the Megamycete, such as Eveline and a replica of the Duke. Rose also receives assistance from an entity calling himself Michael, though she eventually learns it to be the remnant of her father Ethan. After acquiring the crystal, Rose learns that it was actually a trap set by the remnant of Miranda, who lured her into the realm in another attempt to resurrect Eva through her. With help from Ethan, Rose is able to regain her powers and kills Miranda for good. Having been able to meet her father, Rose leaves the realm content with her nature. In the epilogue of both the game and DLC chapter, it is revealed Rose has joined Hound Wolf Squad and uses her abilities to fight BOWs.[13]

The Umbrella Corporation is an American-based international pharmaceutical company in the Resident Evil universe. Founded in 1968 by prominent British royal descendants Oswell E. Spencer and Edward Ashford, along with Dr. James Marcus, it is portrayed in the series as a major international player in pharmaceutical goods and medical supplies, along with more clandestine operations utilizing genetic engineering. Their legitimate status is only a front for their secret research of "bio-organic weapons" (B.O.W.s), developed through the use of a unique mutagenic virus discovered by the company founders known as the Progenitor Virus.[14]

Oswell E. Spencer (オズウェルEスペンサー, Ozuweru E Supensā) is the owner and co-founder of the Umbrella Corporation, a pharmaceutical drug company that secretly manufactures bio-organic weapons.[16] With limited funding to exploit the flower and its virus, Spencer designs a seemingly benevolent front organization known as Umbrella Pharmaceuticals to accrue revenue so that his machinations on the virus may continue. His colleagues, James Marcus and Edward Ashford, join his company.[16] Through a series of betrayals and espionage, Spencer quickly gains control of the company and its research, and sends subordinates to assassinate Marcus and Ashford.[17][18] Spencer conducts some of his company's research in the Arklay Research Facility, located in the Arklay Mountains. He hires George Trevor, a famous architect, to construct a mansion to conceal the facility, however, with Trevor knowing the secret to the mansion he had just built, Spencer has the architect targeted for assassination and proceeds to abduct Trevor's wife and daughter, having them become test subjects for virus research and development.[19] Trevor's daughter Lisa would become a promising specimen for new fields of bio-exploitation, experiencing much torment and mutilations in the process. Spencer's plans progress smoothly until Marcus returns from the dead through the Queen Leech as absorbing his genetic memory,[20] motivated by revenge to destroy one of Spencer's luxury trains and cause a viral outbreak in the Arklay Research Facility.[21] The outbreak spreads throughout the region, sparking the events of Resident Evil Zero and the original Resident Evil. The virus subsequently spreads to Raccoon City during the events of Resident Evil 2 and Resident Evil 3: Nemesis, prompting the U.S. government to attempt to contain the outbreak by ordering the destruction of the city.[22]

After the city's destruction, Spencer attempts to disguise the incident as a government conspiracy by hiring top lawyers and false witnesses. His actions prolong the legal proceedings and allow the Umbrella Corporation to stay afloat for five more years. Ultimately, Albert Wesker betrays Spencer by handing over secret documents to the U.S. government while providing personal testimony in court.[23] Spencer becomes a wanted man and goes into hiding at his mansion in Europe. Wesker kills Spencer before Chris Redfield and Jill Valentine can arrest him.[24]

Carlos Oliveira (カルロスオリヴェイラ, Karurosu Oriveira), the second main character of Resident Evil 3,[32] is a mercenary and a former member of a South American communist guerrilla group. After the government forces wiped out his organization, Carlos was scouted out by the Umbrella Corporation to join Umbrella's UBCS. He joined the force and was assigned to Delta Platoon, Company A (serving alongside Nicholai Ginovaef and Mikhail Victor), which was in charge of heavy firearms and weapons maintenance.[32] Despite his violent background, he is warm-hearted and known for joking around.[33] In Resident Evil 3: Nemesis, Carlos assists Jill Valentine throughout the game as the two of them attempt to escape Raccoon City. After she becomes infected by the T-virus after a battle with the Nemesis, he recovers a vaccine to treat her and successfully escapes the city with Jill. In the remake, Carlos' role as a playable character is expanded upon, including a brief excursion to the Raccoon City Police Department. He also appears as a playable character in The Umbrella Chronicles, where the events of Resident Evil 3 are revisited in the "Raccoon's Destruction" scenario.

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