What is the "est" value in userGWAS output?

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Aoife

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Nov 4, 2025, 11:02:48 AMNov 4
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Hi, 

Is the  "est" (estimated effect) always a standardised beta coefficient in userGWAS() output? 

For context in case it's needed:
- I'm doing a GWAS-by-subtraction with two traits 
- Both original traits sumstats are case/control studies 
- Trait1 GWAS used logistic model, trait2 had binary outcome but z-statistics in sumstats only
- The sumstats () output I created, which is then used in userGWAS, has beta.trait1 and beta.trait2 

Many thanks,
Aoife 
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