Stem cell patent news (12/26/09)

[Sciclips]

WO (PCT) Applications (12/25/09)

1. Selective activation of stem cells in a mixed set of cell types
using microbial opsin
2. Method for differentiating mesenchymal stem cells (MSCs) into
fibroblasts using EGF and TGF-beta receptor agonists
3. Method for promoting hematopoietic stem cell (HSC) growth by up-
regulating nitric oxide (NO) signaling pathway
4. Cripto- 1 as a biomarker for stem cell activity in damaged
myocardial tissues
5. Stem cells for treatment of acute and chronic wounds
6. Treatment of cardiac damage by inducing the secretion of TSG- 6
protein by MSCs

US Patent Applications (12/24/09)

1. Reducing apoptosis of human embryonic stem cells by inhibiting Rho
kinase
2. Enhancing stem cell mobilization by increasing elastase activity
3. Stem cells with modified glycomes on their surfaces
4. Method for the isolation of stem cells using specific binders to
cell surface glycan structures
5. Stem cells expressing microRNA, miR-499, for the treatment of
myocardial infarction
6. Method for treating a progressive neurodegenerative disorder with
bone marrow stem cells
7. Method of making hepatocytes from extrahepatic somatic stem cells.

US Patents Issued (12/22/09)

1. Differentiation of stem cells into the neural cells by culturing in
a medium with EFG and HGF
2. Increased production of hematopoietic stem cells or progenitor cell
production by activating parathyroid hormone/parathyroid hormone-
related protein (PTH/PTHrP) receptor
3. Preparation of developmentally potent mesenchymal stem cells using
substituted deoxynucleotide or deoxynucleoside
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