PTM-SEA: min overlap doesn't filter results

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Tyler Sagendorf

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Nov 4, 2021, 8:17:11 PM11/4/21
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Setting the min overlap to 10, for example, still results in signatures with overlap percent less than 10 in the combined results.

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Nov 4, 2021, 8:17:19 PM11/4/21
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Anthony Castanza

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Nov 4, 2021, 8:23:37 PM11/4/21
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Hello,

 

While GenePattern offers a platform for running PTM-SEA, we don't actually develop it.

I'd recommend reaching out to the authors of PTM-SEA. You might open a ticket at their GitHub repository https://github.com/broadinstitute/ssGSEA2.0.

 

-Anthony

 

Anthony S. Castanza, PhD

Curator, Molecular Signatures Database

Mesirov Lab, Department of Medicine

University of California, San Diego

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