GISTIC2 with public server

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Shota Kato

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Jan 16, 2025, 7:02:42 PMJan 16
to GenePattern Help Forum
Hi, 

I performed GISTIC2 with the public server.
However, the amplification/deletion plots showed a narrow region of chromosome 8 (file attached).
I would like to know how I can solve this problem.

I used a segmentation file from WGS data and the provided hg38 ref file.

Thank you, 
Shota
611424.amp_qplot copy.png

Andrew Cherniack

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Jan 28, 2025, 2:12:32 PMJan 28
to GenePattern Help Forum
Hi

We need to know more about how you ran GISTIC to answer your question.
Can you provide us with your input parameters and seg file?

Andy

Shota Kato

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Jan 28, 2025, 8:15:08 PMJan 28
to GenePattern Help Forum
Hello Andy, 

I used the default parameters with the broad analysis option.
I attached the input seg file.

I appreciate your cooperation.

Best regards,
Shota

2025年1月29日水曜日 4:12:32 UTC+9 Andrew Cherniack:
GISTIC_input.txt
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