Though we tried to remember to take it out of the water and secure it to the top of the boat during the big rapids, it may or may not have taken a ride down the infamous Crystal while clipped to the outside of the rig.
Monkeypox virus (MPXV) is closely related to the infamous variola (smallpox) virus, causing a febrile rash illness in humans similar to but milder than smallpox. In the twentieth century, human monkeypox had been mostly a rare zoonotic disease confined to forested areas in West and Central Africa. However, the case number and geographic range have increased significantly in this century, coincided with the waning of the smallpox vaccine-induced immunity in the global population. The outbreak of human monkeypox in multiple countries since May 2022 has been unusual in its large case number and the absence of direct links to endemic countries, raising concerns for a possible change in monkeypox transmission pattern that could pose a greater global threat. Here, we review aspects of MPXV biology that are relevant for risk assessment and preparedness for a monkeypox epidemic, with an emphasis on recent progress in understanding of the virus host range, evolutionary potential, and neutralization targets.
Lisette, a Saint-Domingue-born Creole slave and daughter of an African-born bossale, has inherited not only the condition of slavery but the traumatic memory of the Middle Passage as well. The stories told to her by her grandmother and godmother, including the horrific voyage aboard the infamous slave ship Rosalie, have become part of her own story, the one she tells in this haunting novel by the acclaimed Haitian writer Évelyne Trouillot.
a 16c. merger of two Middle English words, with the form of infamous "not well-known" (early 15c.) and the sense of infamis (late 14c.), "of ill repute, famous for badness." Infamous is from Medieval Latin infamosus, from in- "not, opposite of" (see in- (1)) + Latin famosus "celebrated" (see famous). Infamis is from Latin infamis "of ill fame" (see infamy).
Meaning "causing infamy" is from 1550s. As a legal term, "disqualified from certain rights of citizens because of conviction for certain crimes" (late 14c.). The neutral fameless (in the sense original to infamous) is recorded from 1590s. Related: Infamously.
late 14c., "celebrated in public report, renowned, well-known" also "notorious, infamous," from Anglo-French famous, Old French fameus (Modern French fameux), from Latin famosus "much talked of, renowned," often "infamous, notorious, of ill repute," from fama (from PIE root *bha- (2) "to speak, tell, say"). A native word for this was Old English namcuð, literally "name-known." Catch phrase famous last words in the humorous sense "remark likely to prove fatally wrong" is attested from 1921 (early lists of them include "Let's see if it's loaded ... We'll get across before the train comes ... Which one is the third rail? ... Light up, it can't explode").
early 15c., "public disgrace, dishonor, evil fame," from Old French infamie "dishonor, infamous person" (14c.) and directly from Latin infamia "ill fame, bad repute, dishonor," from infamis "disreputable, notorious, of ill fame," from in- "not, without" (see in- (1)) + fama "reputation" (from PIE root *bha- (2) "to speak, tell, say"). Meaning "quality of being shamefully vile" is from 1510s.
And commenting systems