ERROR: 5 (Error from lead SNPs and candidate SNPs identification / No significant SNPs were identified)
This error can occur when no candidate SNPs were identified. Note that indels
are included in the FUMA from v1.3.0 but both alleles need to match exactly
with selected reference panel. MHC region is also excluded by default. 1. If
there is no significant hit at your defined P-value cutoff for lead SNPs and
GWAS tagged SNPs, you can try to use a less stringent P-value threshold or
provide predefined lead SNPs. 2. If there are significant SNPs with very low
minor allele frequency, try decreasing MAF threshold (default 0.01). Manhattan
plots and significant top 10 SNPs in your input file are available from SNP2GENE.
RSID | GENE | CHR | BP | A1 | TEST | NMISS | OR | SE | L95 | U95 | STAT | P |
rs10414271 | --- | 19 | 31958905 | C | ADD | 181 | 0.1823 | 0.4659 | 0.07313 | 0.4542 | -3.654 | 0.000259 |
rs11100042 | --- | 4 | 1.57E+08 | C | ADD | 182 | 5.341 | 0.4044 | 2.418 | 11.8 | 4.143 | 3.42E-05 |