MAGMA Gene set enrichment analysis using uploaded summary stats

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Per Qvist

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Dec 19, 2018, 7:21:52 AM12/19/18
to FUMA GWAS users

Could you consider adding a MAGMA gene-set enrichment analysis option to the gene2function pipeline?
It would be particularly useful, if users could upload their own summary stats like in the SNP2gene pipeline.

Thanks for a great tool!

Kyoko Watanabe

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Dec 19, 2018, 8:36:52 AM12/19/18
to FUMA GWAS users
Hi Per,

Thank you for your suggestions.
However, MAGMA analysis is not suitable for GENE2FUNC since MAGMA requires sumstats while input of GENE2FUNC process is just a list of genes.
MAGMA gene-set analysis is performed as part of SNP2GENE, Are you asking this because you don't want to run entire SNP2GENE process but only MAGMA gene-set analysis?
I could separate MAGMA from SNP2GENE but if you just want to run MAGMA, it might be faster/easier to run MAGMA command line (it's very easy to use software, https://ctg.cncr.nl/software/magma).

Best,
Kyoko
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