Question about direction in tutorial#parameters

[Siyi Liu]

Hi Tanya,

Thanks for maintaining this forum.

I would like to ask about the description of the direction for Maximum GWAS P-value.  As is stated in the SNP2GENE page, setting this parameter to 1 would include all SNPs in LD with the lead SNP for annotation (as candidate SNPs); Hence, the higher parameter should increase the number of candidate SNPs, not decrease it. Similarly, in the section of eQTL mapping, a lower eQTL maximum p-value (more strict) should produce fewer mapped genes. I would like to know if my interpretation is correct, or if it was a typo on the website?

Thanks for your time and patience.

Best regards,

Siyi