Drug dosage adjustment in renal failure
Jim Busser
http://www.bmj.com/cgi/content/full/bmj;331/7511/263
They assessed four references, on 100 drugs:
> We further examined how drugs that required no adjustment according to one source were categorised by a second source (table 4). The differences were remarkable—for example, 11 drugs (26%) out of 43 for which the BNFrecommended no adjustment were categorised by Martindale as requiring it (dexamethasone, prednisone, methylprednisolone, hydrocortisone, paracetamol, amiodarone, promethazine, isosorbide mononitrate, isosorbidedinitrate, progesterone, loratadine).
> ...
> In seven instances (six drugs) a drug that required no adjustment according to one source was categorised as contraindicated in patients with impaired renal function by a second source (table 4).
What is the FD source of "truth" ... I am having trouble finding anything at Dialysis Clinics international (DCI) if that is what FD "DCI" means...
I also found no data file, but:
Dalhousie University Drug Information Resources
http://dir.pharmacy.dal.ca/renal.php
From Clinical Pharmacology Department, Christchurch Hospital, New Zealand
http://www.rphworld.com/pharmacist/viewlink-25463.html
Clinician's Ultimate Reference
http://www.globalrph.com/renaldosing2.htm
-- Jim
Jim Busser
> (DCI) if that is what FD "DCI" means...
Oops I think it just means "INN"
http://dictionary.reverso.net/medical-french-english/DCI
... maybe save this link for translating!
however my questions about 'source of truth" for adjustment for renal failure remain legitimate.
-- Jim
Eric MAEKER
> anything at Dialysis Clinics international (DCI) if that is what FD
> "DCI" means...
DCI (Dénomination Commune Internationale) is the french translation of
INN. FD comes without any references to :
- ICD 10
- Pregnancy datas
- Physiological limits
Users have to define themselves. Then the datas can be transmitted
anounymously to a server and be reintroduced into the next release of
FD.
For now, there are no users to participate...
Eric