Well no, not really?
Still people will usually prefer one or the other. I’ve seen some folks make capsules with crushed E and MDMA combined. Purchase Dutch Champagne MDMA Crystal in Australia
https://au-psychedelics.com/product-category/mugs/
https://au-psychedelics.com/product/purchase-dutch-champagne-mdma-crystal/
So major tip, if you’re experimenting with pressed pills, TAKE A QUARTER OR HALF FIRST, they were literally designed to be more potent. Pressed pills were the norm in the 90s and early 2000s, from people I’ve talked to, some colors would give you different effects. I’ve been told Green ones were akin to an Indica experience. (Haven’t personally experienced