Buy AB-CHMINACA crystal
Buy AB-CHMINACA crystal also 1-(cyclohexylmethyl)-1H-indazole-3- carboxamide. (AB-CHMINACA). is an indazole-based synthetic cannabinoid. It is a potent agonist of the CB1 receptor (Ki = 0.78 nM) and CB2 receptor (Ki = 0.45 nM) and fully substitutes for ?9-THC in rat discrimination studies, while being 16x more potent.
it contains a valine amino acid amide residue as part of its structure, where older cannabinoids contained a naphthyl or adamantane residue.
Formula:
C20H28N4O2
ChemSpider ID:
30646774
IUPAC name
N-[(2S)-1-Amino-3-methyl-1-oxobutan-2-yl]-1-(cyclohexylmethyl)indazole-3-carboxamide
An Analytical Reference Standard
Item No.
28236
Purity:
?98%
Formulation:
A crystalline solid
ADB-CHMINACA (MAB-CHMINACA)
is a new synthetic cannabinoid with high potency and many reported adverse events and fatalities. The drug is currently scheduled in several countries in Europe and the USA.
Analyse
Analyse method developed to confirm ADB-CHMINACA intake for clinical and forensic programs. For many synthetic cannabinoids, parent compound is not detectable in biological samples after intake, making the detection of metabolites the only way to prove consumption. Therefore, detection of ADB-CHMINACA metabolites in biological specimens is critical.
Part Description
LP262538-4 AB-CHMINACA butanoate
AB-CHMINACA hydroxycyclohexyl and AB-CHMINACA butanoate are metabolites of AB-CHMINACA (N-[1-amino-3-methyl-oxobutan-2-yl]-1-[cyclohexylmethyl]-1H-indazole-3-carboxamide), an indazole-based synthetic cannabinoid that shows high affinity for cannabinoid CB1 and CB2 receptors.
Synthetic cannabinoids interact with the same brain receptors as THC (the active drug present in marijuana) and have been demonstrated to produce similar effects. The drug is typically sprayed on botanical material and smoked, although it can be ingested in liquid or also powder form. Products containing this drug are sold under a wide variety of names including (but not limited to) Spice, Potpourri, Smoke, K2, Zombie, Kush, and Cloud 10.
Related Names
Cfm
Cloud 10
CNFR
CNFRM
Conf
Confirmation
Confirmatory
DRUG/TOXICOLOGY
Drugs
GCMS
K2
Ordinal
Point in time
Potpourri
PR
QL
Qual
Qualitative
Random
Screen
Spice
Synthetic cannabinoid
UA
UR
Urn
Zombie
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BUY 5FUR-144 POWDER
BUY 5FUR-144 POWDER XLR-11 (5?-fluoro-UR-144) is a drug that acts as a potent agonist for the cannabinoid receptors CB1 and CB2 with EC50 values of 98 nM and 83 nM, respectively.
It is a 3-(tetramethylcyclopropylmethanoyl)indole derivative related to compounds such as UR-144, A-796,260 and A-834,735, but it is not specifically listed in the patent or scientific literature alongside these other similar compounds, and appears to have not previously been made by Abbott Laboratories, despite falling within the claims of patent WO 2006/069196. XLR-11 was found to produce rapid, short-lived hypothermic effects in rats at doses of 3 mg/kg and 10 mg/kg, suggesting that it is of comparable potency to APICA and STS-135.
Detection
A forensic standard for this compound is available, and a representative mass spectrum has been posted on Forendex.
Side effects
XLR-11 has been linked to hospitalizations due to its use.
Recreational use
XLR-11 was instead first identified by laboratories in 2012 as an ingredient in synthetic cannabis smoking blends, and appears to be a novel compound invented specifically for grey-market recreational use.
Chemical and physical data
Formula: C21H28FNO
Molar mass: 329.459 g·mol?1
See also
FAB-144
JWH-018
STS-135
UR-144
XLR-12
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Buy 5fur-144 CRYSTAL
Buy 5fur-144 CRYSTAL (XLR-11 or 5?-fluoro-UR-144) is a drug that acts as a potent agonist for the cannabinoid receptors CB1 and CB2 with EC50 values of 98 nM and 83 nM, respectively.
It is a 3-(tetramethylcyclopropylmethanoyl)indole derivative related to compounds such as UR-144, A-796,260 and A-834,735, but it is not specifically listed in the patent or scientific literature alongside these other similar compounds, and appears to have not previously been made by Abbott Laboratories, despite falling within the claims of patent WO 2006/069196. XLR-11 was found to produce rapid, short-lived hypothermic effects in rats at doses of 3 mg/kg and 10 mg/kg, suggesting that it is of comparable potency to APICA and STS-135.
Chemical and physical data
Formula: C21H28FNO
Molar mass: 329.459 g·mol?1
Detection
A forensic standard for this compound is available, and a representative mass spectrum has been posted on Forendex
Side effects
XLR-11 has been linked to hospitalizations due to its use
Toxicity
XLR-11 has been linked to acute kidney injury in some users, along with AM-2201.
Legal Status
XLR-11 was banned in New Zealand by being added to the temporary class drug schedule, effective from 13 July 2012.
The U.S. Drug Enforcement Administration (DEA) made the synthetic cannabinoids UR-144, XLR11, and AKB48 Schedule I, illegal drugs under the Controlled Substances Act (CSA) for the next two years as of 16 May 2013.
It has also been banned in Florida as of December 11, 2012.
Arizona banned XLR-11 on 3 April 2013.
As of October 2015 XLR-11 is a controlled substance in China.
XLR-11 is banned in the Czech Republic
See also
FAB-144
JWH-018
STS-135
UR-144
XLR-12
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Buy 5F-PB22 Crystal
Buy 5F-PB22 Crystal is a designer drug which acts as a cannabinoid agonist. The structure of 5F-PB-22 appears to have been designed with an understanding of structure–activity relationships within the indole class of cannabinoids.
5-fluoro PB-22 (Item No. 14095) is an analytical reference material that is structurally categorized as a synthetic cannabinoid (CB). It is a full agonist of human CB1 and CB2 receptors (pEC50s = 8.55 and 7.97, respectively).1,2 5-fluoro PB-22 potently and dose-dependently induces hypothermia and reduces heart rate in rats, mimicking the in vivo effects of ?9-THC (Item Nos. 12068 | ISO6157).1 This product is intended for research and forensic applications.
Pharmacology
5F-PB-22 acts as a full agonist with a binding affinity of 0.468 nM at CB1 and 0.633 nM at CB2 cannabinoid receptors.
Chemical and physical data
Formula: C23H21FN2O2
Molar mass: 376.431 g·mol?1
Technical Information
Formal Name1-(5-fluoropentyl)-8-quinolinyl ester-1H-indole-3-carboxylic acid
CAS Number1400742-41-7
Molecular FormulaC23H21FN2O2
Formula Weight376.4
Purity?98%
FormulationA neat solid
SMILESO=C(OC1=C(N=CC=C2)C2=CC=C1)C3=CN(CCCCCF)C4=C3C=CC=C4
InChi CodeInChI=1S/C23H21FN2O2/c24-13-4-1-5-15-26-16-19(18-10-2-3-11-20(18)26)23(27)28-21-12-6-8-17-9-7-14-25-22(17)21/h2-3,6-12,14,16H,1,4-5,13,15H2
InChi KeyMBOCMBFDYVSGLJ-UHFFFAOYSA-N
WARNING This product is not for human or veterinary use.
Shipping & Storage Information
Storage: -20°C
Shipping: Room Temperature in continental US; may vary elsewhere
Stability: ? 3 years
See also
AM-2201
JWH-018
QUCHIC
QUPIC
SDB-001
SDB-005
Buy 5f-mdmb-2201 online
Buy 5f-mdmb-2201 online synthetic cannabinoid also known as 5F-MMB-PICA, 5F-AMB-PICA, and I-AMB.
Synonyms MDMB-2201 5-fluoro-MDMB-2201
CAS Number 1971007-88-1
Molecular Formula C21H29FN2O3
Formula Weight 376.5
Purity ?100%
Formulation A crystalline solid ?max 217, 290 nm
Control Status 5f mdmb 2201
5F-MDMB-PICA is a Schedule I controlled substance under the Federal Controlled Substances Act.
IllicitBuy 5f-mdmb-2201 online :
The National Forensic Laboratory Information System (NFLIS), a system that collects drug analysis information from state and local forensic laboratories, contain 340 reports for 5F-MDMB-PICA between 2016 and 2018.
Storage Information
Storage: -20°C
Shipping : Room Temperature in continental US; may vary elsewhere
Stability: ? 2 years
Pharmacology:
Data from preclinical studies show that 5F-MDMBPICA binds to and acts as an agonist at the CB1 receptor. There are no published studies on the safety of 5FMDMB-PICA for human use.
MMB-2201 is the indole core analogue of 5F-AMB. Synthetic cannabinoid compounds with an indole-3-carboxamide or indazole-3-carboxamide core bearing a N-1-methoxycarbonyl group with attached isopropyl or tert-butyl substituent, have proved to be much more dangerous than older synthetic cannabinoid compounds previously reported, and have been linked to many deaths in Russia, Japan, Europe and the United States.
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Buy 5F-BB22 Crystal is an analytical reference material that is structurally categorized as a synthetic cannabinoid (CB). It is a full agonist of human CB1 and CB2 receptors (pEC50s = 8.55 and 7.97, respectively).1,2 5-fluoro PB-22 potently and dose-dependently induces hypothermia and reduces heart rate in rats, mimicking the in vivo effects of ?9-THC.1 This product is intended for research and forensic applications.
Pharmacology
5F-BB22 acts as a full agonist with a binding affinity of 1.94 nM at CB1 and 0.266 nM at CB2 cannabinoid receptors.
Those of you who are in the market for high-grade synthetic cannabinoid powder or Crystals for sale can easily find it at croweed. The purity of our products is without equal, not to mention how varied our range of supplements is. It includes much more than just traditional THC and CBD so that you can make your research complete.
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BUY 5F-AKB48 POWDER (also known as 5F-AKB-48 or 5F-APINACA) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005 but with a 5-fluoropentyl chain on the indazole 1-position, and 5F-APINACA falls within the claims of this patent, as despite not being disclosed as an example, it is very similar to the corresponding pentanenitrile and 4-chlorobutyl compounds which are claimed as examples 3 and 4. In the United States, 5F-AKB48 is a Schedule I controlled substance.
5F-AKB48 is an Anlage II controlled drug in Germany since July 2013. As of October 2015, 5F-AKB48 is a controlled substance in China.
5F-AKB48 is banned in the Czech Republic.
5F-AKB48 was first identified in South Korea. It is expected to be a potent agonist of the CB1 receptor and CB2 receptor. Its metabolism has been described in literature.
Chemical and physical data
Formula: C23H30FN3O
Molar mass: 383.5 g/mol g·mol?1
Pharmacology
5F-AKB48 acts as a full agonist with a binding affinity of 1.94 nM at CB1 and 0.266 nM at CB2 cannabinoid receptors.
See also
5F-ADB
5F-AMB
AB-FUBINACA
AB-CHFUPYCA
AB-PINACA
ADB-CHMINACA
ADB-FUBINACA
ADB-PINACA
ADBICA
APICA
APINACA
FUB-APINACA
MDMB-CHMICA
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Buy 3-fpm ( 3-Fluorophenmetrazine ), Buy 3-fpm crystalline powder
Buy 3-fpm crystalline powder (also known as 3-FPM, 3-FPH and PAL-593) is a phenylmorpholine-based stimulant and fluorinated analogue of phenmetrazine that has been sold online as a designer drug.
Stereoisomers
3-FPM is a derivative of phenmetrazine. As described by McLaughlin and colleagues
(7), “the fluorinated analogs of phenmetrazine contain two chiral centers which yield the potential for four stereoisomers and two racemic mixtures (i.e., cis- and trans-racemates)
Physical appearance
3-Fluorophenmetrazine is a white, solid, crystalline powder. It was also identified in
yellow, blue or green pellets (tablets).
Chemical name
IUPAC name: 2-(3-fluorophenyl)-3-methylmorpholine; hydrochloride.
Identification and analysis
A number of analytical tests have been used to differentiate 3-FPM from its positional isomers, 2- and 4-FPM, including gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, and thin-layer chromatography (7). All of the methods successfully differentiated 3-FPM from its.
Pharmacodynamics
3-FPM is potent at releasing dopamine (DA) and norepinephrine (NE), with half
maximal effective concentration (EC50) values of 43 and 30 nM, respectively, and
less potent at releasing serotonin (5-HT; 2558 nM (1)).
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