Depends on the severity of the hazard. Swiss Army Knife vs AK 47; STEC
vs Listeria innocua; matrix: Ice cream vs lettuce. "How lucky do you
feel . . ."
Several decades ago, Lester Crawford said that when he was at FDA they
opined that "one in a million" seemed about right. But in the
following decades more objective approaches have been published.
Here's one:
Coleman, M. , Elkins, C. , Gutting, B. , Mongodin, E. , Solano
Aguilar, G. and Walls, I. (2018), Microbiota and Dose Response:
Evolving Paradigm of Health Triangle. Risk Analysis, 38: 2013-2028.
doi:10.1111/risa.13121
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