Prof. Richard Benton (www.unil.ch/cig/benton) and Dr Thomas Auer at the Center for Integrative Genomics at the University of Lausanne are seeking a PhD student with a strong background and interest in neurobiology, molecular genetics and evolution.
Expected start date in position : 01.01.2020 / to be agreed
Contract length : 1 year, renewable max 4 years with a possible extension
Activity rate : 100%
Workplace : University of Lausanne, Dorigny
About the position
How
animals’ extraordinarily diverse behaviours have evolved is unknown.
Relating interspecific behavioural differences to anatomical or
physiological distinctions in neural circuits, and causal genetic
variation, offers a powerful approach to inform how nervous systems
develop, function and change.
We have established a new model neurogenetic system, Drosophila sechellia, an island endemic that is closely related to the powerful laboratory model D. melanogaster. While D. sechellia
retains global genomic and superficial morphological similarity to its
cosmopolitan, generalist cousin, this species has adapted to a unique
ecological niche, using Morinda fruit as a sole host for
feeding and breeding. This species therefore offers an exceptional
experimental system for comparative neuroscience.
The
candidate will develop her/his project within the gustatory system of
these drosophilid species to determine the molecular and neural
mechanisms that explain the distinct feeding behaviours of these
animals. The project will involve a combination of molecular genetics,
genome engineering, transcriptomics, circuit mapping, neural imaging,
and behavioural analysis.
Relevant references
Auer et al., bioRxiv (2019) www.biorxiv.org/content/10.1101/546507v1
Prieto-Godino et al., Neuron (2017) 93: 661-676
Prieto-Godino et al., Nature (2016) 539: 93-97
Your qualifications
The Center for Integrative Genomics encompasses 15 research labs investigating diverse fields related to functional genomics, and offers state-of-the-art experimental facilities. Beyond the training in the host laboratory, numerous possibilities exist at UNIL for further professional education (e.g., in bioinformatics, imaging, soft-skills, career development).
Contact for further informationDeadline: 31.01.2020