I wouldn't, unless (most of) your blobs are close in size to multiples
of (32 KiB - x bytes) (where x is the overhead of the headers of a blob
page, which I don't know by heart), or if your PK index is very deep on
other page sizes.
Otherwise, you'll probably just waste more space, with (on average) half
empty blob pages for the last page of each blob.
As an aside, "segment size N" is pretty much irrelevant these days.
Mark
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Mark Rotteveel