"that may be or deserves to be despised," 1550s, from Late Latin despicabilis, from Latin despicari "despise, disdain," which is related to despicere "to look down upon," from de- "down" (see de-) + spicere, variant of specere "to look at" (from PIE root *spek- "to observe"). Related: Despicability; despicably; despicableness.
Villainous Gru lives up to his reputation as a despicable, deplorable and downright unlikable guy when he hatches a plan to steal the moon from the sky. But he has a tough time staying on task after three orphans land in his care.
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