Testing for simple population branching - No output produced

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Maria

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Aug 21, 2024, 10:05:54 AM8/21/24
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Dear users,

I am having problems running a simple analysis perhaps someone can help here.

I am using fsc26 and SFS stats that I obtained with easySFS. I have 4 populations and want depict a simple branching topology with no migration. This is my command:

/cluster/home/s_menb/software/fsc26_linux64/fsc26 -t model_1_braya.tpl -e model_1_braya.est -E 1 -m -0 -C 10 -n 10000 -L 40 -s 0 -M --multiSFS -x -d -c 64 -B 64

See below the scenario topology, .est and .tpl file.

 google_group.png

 model_1_braya.est

// Search ranges and rules file

// ****************************

//$NPOP0$

//$NPOP1$

//$NPOP2$

//$NPOP3$

 

[PARAMETERS]

//#isInt? #name   #dist.#min  #max

//all Ns are in number of haploid individuals

1  $TDIV$        unif     300000  400000   output

1  $TIME1$       unif     20000   40000    output

1  $TIME2$       unif     4000    3000    output

1  $NANC$        unif     10      1e7      output

1  $NPOP0$       unif     10      1e7      output

1  $NPOP1$       unif     10      1e7      output

1  $NPOP2$       unif     10      1e7      output

1  $NPOP3$       unif     10      1e7      output

 

[RULES]

1  $TDIV$ > $TIME1$

1  $TIME1$ > $TIME2$

 

model_1_braya.tpl

//Parameters for the coalescence simulation program : simcoal.exe

4 samples to simulate :

//Population effective sizes (number of genes)

$NPOP0$

$NPOP1$

$NPOP2$

$NPOP3$

//Samples sizes and samples age

35

14

27

14

//Growth rates: negative growth implies population expansion

0

0

0

0

//Number of migration matrices : 0 implies no migration between demes

0

//historical event: time, source, sink, migrants, new deme size, growth rate, migr mat index

3 historical event

$TIME2$     1 2 0 1 0 0

$TIME1$     3 1 0 1 0 0

$TDIV$      0 3 0 1 0 0

//Number of independent loci [chromosome]

1 0

//Per chromosome: Number of contiguous linkage Block: a block is a set of contiguous loci

1

//per Block:data type, number of loci, per gen recomb and mut rates

SNP 1448 0 5.77e-9

 

The program has been running for 8 days. It has written the sim and parm files but no output produced.  For such a small dataset and based on previous experience with fsc26 I assume the programme is just hanging and stuck.

Does anyone have a suggestion where to look for a mistake possibly in the files?

Best regards,

Maria

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