Is using -S option vs -d0 option with same seed number doing the same underlying simulation?

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Daiiivid Gao

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Jul 8, 2025, 8:38:18 AMJul 8
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Hi all,
I'm testing statistical properties of fastsimcoal vs another software which requires full DNA sequences. I first simulate the genetic data using -S for the other software and -d0 fastsimcoal respectively. Given that I use the same seed number, are the underlying simulation the same, just differing by output format? I analyzed the output but the allele counts didn't match, but maybe that's due to me not able to figure out the number of mutations per site has gone through.

Thank you,
David
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