N and C Terminal positions

[Jerven Bolleman]

Hi Everyone,

I would like to add the following two classes to FALDO. This is
important for use inside UniProt, but can be helpful for other users
as well. What do you guys think?

Regards,
Jerven

:N-TerminalPosition
rdf:type owl:Class ;
rdfs:subClassOf :ExactPosition ;
rdfs:comment "The position of the starting amino-acid a protein or
polypeptide terminated by an amino acid with a free amine group
(-NH2). The convention for writing peptide sequences is to put the
N-terminus on the left and write the sequence from N- to C-terminus.
Instances of this class are often used when the reference sequence is
not complete "^^xsd:string ;
rdfs:seeAlso <http://en.wikipedia.org/wiki/N-terminus> ;
owl:disjointWith :C-TerminalPosition .

:C-TerminalPosition
rdf:type owl:Class ;
rdfs:subClassOf :ExactPosition ;
rdfs:comment "The C-terminus is the end of an amino acid chain
(protein or polypeptide), terminated by a free carboxyl group
(-COOH)."^^xsd:string ;
rdfs:seeAlso <http://en.wikipedia.org/wiki/C-terminus> ;
owl:disjointWith :N-TerminalPosition .


--
Jerven Bolleman
m...@jerven.eu

[Michel Dumontier]

Sounds good - this links up with SIO nicely (as subclasses of SIO concepts)
http://semanticscience.org/resource/start-position
http://semanticscience.org/resource/end-position

m.
Michel Dumontier
Associate Professor of Medicine (Biomedical Informatics), Stanford University
Chair, W3C Semantic Web for Health Care and the Life Sciences Interest Group
http://dumontierlab.com

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