I’ve updated to the latest current channel version of Excel
Microsoft® Excel® for Microsoft 365 MSO (Version 2505 Build 16.0.18827.20102) 64-bit
It looks like you have a slightly newer build, but not much.
I don’t see any problem with a simple add-in (built with v1.9.0-beta2) that does include a ribbon (so gets the Application object and loads the extra COM add-in during startup).
I have the add-in installed, so it loads automatically when Excel starts.
Multiple Excel processes start without problem.
What is the simplest add-in that reproduces the issue for you?
Does your add-in do anything exciting in the AutoOpen or the ribbon class loading?
I presume when starting from the Alt+taskbar click that you see the little “Do you want to start a new instance of Excel?” dialog, and you don’t see this when starting with “/x” from the shortcut?
-Govert
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Your error is an Access Violation (code 0xc0000005) in the Excel process. The appearance of “ntdll.dll” is just how the error is surfaced, and this Windows library is not likely to be involved.
I don’t know whether “OFFICE_MODULE_VERSION_MISMATCH” is a clue – I do see a few Google hits though nothing specific. It might be a diagnostic that Office runs after a crash, or something more indicative of the issue. Here’s an unrelated example discussion where it appeared recently Addin crashing on Current Channel Preview - Version 2505 Build 16.0.18827.20008 · Issue #5702 · OfficeDev/office-js.
From what you report, it seems an Office update might have broken this. Certainly you should report it with the Send a Frown button if you can.
Is the pattern of launching with the Alt-key detection for a new instance something your users are likely to do often? If not, it’s hard to tell how prevalent the issue is. I’ve certainly not heard of this behaviour before. In recent versions, when an Excel-DNA project is started in the VS debugger, a new process is started with the “/x” argument. But it sounds like this is not the error case you see.
I would suggest you go through the various Office repair options to see it that might help. Otherwise you can try older Office versions by either changing the update channel (Change the Microsoft 365 Apps update channel for devices in your organization - Microsoft 365 Apps | Microsoft Learn) or by reverting to a specific earlier version (How to revert to an earlier version of Office - Microsoft Support).
I suspect it’s something that goes wrong with a particular Office update sequence, or a version you have with some features flags enabled from Microsoft’s side.
Regards,
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On Jun 17, 2025, at 2:50 PM, Govert van Drimmelen <govert.va...@gmail.com> wrote:
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