I am guessing, based on what Freeman Dyson once wrote, is that scientists rely on new and improved equipment and can use these to discover new phenomena, and test hypotheses. Based on his judgement, I am guessing that we have hit a financial barrier, where to make huge and different discoveries, we'll need a bigger boat, a bigger telescope, and more power accelerator, or neutrino interceptor, a super LIGO. Hang some of these super detectors at the far edge of the solar system and I suspect we'll uncover the "unexpected." Stuff, that may not fit neatly into General Relativity or the quantum. In my imagination, this stuff would be kilometers long, and cost 100's of billions of dollars, yuans, ecu's to get into position and be operated mostly by machine intelligence. No need for life support. Cheaper.