Hartl And Jones Genetics 7th Edition
Gregory Muench
The book is divided into 18 chapters that guide the reader through the diverse topics that make up modern genetics. Chapter 1 is an overview of genetics and introduces the basic concepts of molecular genetics. Chapter 2 is an overview of DNA from the brilliant discovery of the double-helical DNA structure by Watson and Crick to the use of DNA markers for genetic mapping and the discovery of disease genes. In Chapters 3 through 5, the authors focus on transmission genetics, chromosome and sex-chromosome inheritance, genetic linkage, and chromosome mapping. Chapters 6 through 8 provide an in-depth description of the molecular biology of DNA replication and recombination, chromosome organization, human karyotypes, and chromosomal behavior. Chapter 9 is devoted to the genetics of bacteria and their viruses. Chapters 10 and 11 cover gene expression and gene regulation. Chapter 12 covers some of the most recent studies in genomics, proteomics, and transgenics. Although this is the chapter that focuses on genomics, much important information learned from the Human Genome Project is provided throughout the book whenever appropriate. For example, in a table on page 410 in chapter 10 showing the characteristics of human transcripts, the source is a Lander paper published in 2001 reporting the results from the Human Genome Project. In Chapter 15, which is about the cell cycle, a transcriptome profile of 800 yeast genes during different phases of the cell cycle is shown. Chapter 13 deals with the genetic control of development in animals and plants as well as important experimental systems such as the nematode and Drosophila. Chapters 14 and 15 discuss the molecular mechanisms of gene mutation, DNA repair, the cell cycle, and cancer. Chapter 16, which focuses on mitochondrial DNA and extranuclear inheritance, should also be of great interest to cancer researchers, although this chapter does not consider the role of mitochondria in cancer. Chapter 17 is on molecular evolution and population genetics. As the last chapter of the book, Chapter 18 provides readers with a dose of reality, focusing on the genetic basis of complex traits and inheritance.
Ogilvie, M. B. & Choquette, C. J. Nettie Maria Stevens (1861-1912): Her Life and Contributions to Cytogenetics. Proceedings of the American Philosophical Society 125, 292-311 (1981).
This textbook brings together advances in the understanding of how bacteria cause disease. Research has changed the way scientists view host-bacterium interactions. The interactions involve immunology, cell biology, human and bacterial physiology, molecular biology and genetics. The six introductory chapters provide the scientific background necessary for exploring the bacterial diseases covered in the book. Through studying the bacteria and diseases presented, the book aims to help students gain knowledge of host-parasite interactions, and examine a range of epidemiological and therapeutic problems.
Mitosis is one of the most fundamental processes in living cells, being common to all eukaryotes, from the simplest plants to the most complex mammals. Its understanding is relevant to virtually every area of biology, ranging from the molecular sciences of cell biology, developmental biology, and genetics to taxonomy and evolutionary studies.
The ability to band chromosomes is of obvious and proven practical value in cytogenetics, but in addition, the fact that chromosomes can be banded suggests that they are highly organised structures and that this compartmentalisation reflects fundamental aspects of chromosome function and how the nucleus handles the genome. It is this facet of chromosome banding that is pursued in this book, drawing mainly on studies of mammalian chromosomes but where appropriate introducing work on chromosomes from other organisms. The subject is approached from the point of view of cell biology, which is not an area often considered by those using chromosome banding in a practical way.
Genetics and Analysis of Quantitative Traits brings together the diverse array of theoretical and empirical applications of quantitative genetics under one cover, in a way that is both comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics. What was originally envisioned as a single text has now become two, with the focus of this first book being on the basic biology and methods of analysis of quantitative characters. (The second book, Evolution and Selection of Quantitative Traits, will address the basic principles that govern the evolutionary dynamics of quantitative characters under the forces of mutation, random genetic drift, and natural and/or artificial selection, integrating the theory of evolution of such characters with existing empirical data from natural and domesticated plant and animal populations.) Written as a general text in quantitative genetics, the book will also be useful as a basic reference for the seasoned professional. Throughout, central theoretical concepts are developed from first principles. To aid the less statistically sophisticated reader, several chapters and appendices focus on the basic statistical tools needed to digest the book. Wherever possible, theoretical and analytical concepts are illustrated with empirical examples from diverse settings.
Emphasizing genes and molecular mechanisms operating in human diseases, this sixth edition textbook introduces the fundamental principles of human genetics. Twenty chapters cover the chromosomal basis of heredity, structure and function of genes and chromosomes, tools of molecular genetics, patterns of single-gene inheritance, genetic variation in individuals and populations, gene mapping, principles of clinical cytogenetics, and disorders of the autosomes and the sex chromosomes. New to this edition is a set of clinical case studies detailing general principles of disease inheritance, pathogenesis, diagnosis, management, and counseling. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Institut fur Humangenetik und Anthropologie, Heidelberg, Germany. Third edition of an extensive textbook on the concepts and problems of human and medical genetics, for geneticists, biomedical researchers, physicians, and epidemiologists. Previous edition 1986. Emphasizes molecular concepts and techniques.
This text integrates coverage of theoretical issues with a clear presentation of experimental population genetics and empirical data. By drawing examples from both recent and classic studies, and by using a variety of organisms to illustrate the phenomena of population genetics, Genetics of Populations, Third Edition, provides students and researchers with the most comprehensive resource available.
Harvard Univ., Boston, MA. Textbook designed for shorter, less comprehensive introductory courses in genetics. Covers basic processes of gene transmission, regulation, mutation, and expression in a clear manner. Abundant color illustrations are included.
A revised and updated fifth edition containing an additional chapter on the impact genetics has on our daily lives. The book reviews the basic concepts of cell and molecular biology with increased coverage of DNA replication and protein synthesis. At the end of ecery chapter a new solved problem that integrates seceral genetics principles appears. This will show students how genetic principles work together to solve problmes an will give students practice reapplying principles learned earlier. Additional to this text one can also aquire a study guide/solutions manual, overhead transparencies and printed and computerized test banks for the IBM or MAC.
Written by two renowned authorities in the field, Genetics, Sixth Edition provides the most current, clear, comprehensive, and balanced introduction to genetics and genomics at the college level. It treats transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects, and provides students with an unprecedented understanding of the basic processes of gene transmission, mutation, expression, and regulation. The text also explores the connections between modern and historical experimental methods used by geneticists, and offers valuable insight into the important historical and social context of genetics and genomics.
The Manual includes 34 detailed experiments with step-by-step protocols and easy-to-follow diagrams that demonstrate major concepts in experimental bacterial genetics. The experiments cover the essential points of mutagenesis, gene transfer, transposable elements, and gene fusions and are accomplished with a set of 44 bacterial strains.
This book features more than 100 expert authors from around the world and offers the full range of scientific and clinical perspectives needed to create this unique, comprehensive overview of Cryptococcus. It covers both the Cryptococcus neoformans and Cryptococcus gattii species, examining in detail the life cycle, pathophysiology, molecular biology, genetics, genomics, epidemiology, immunology, and clinical management of this encapsulated yeast. Among the 44 chapters, readers will find several in-depth discussions of theC. gattii outbreak that began on Vancouver Island in 1999 and then spread into the mainland of Canada and the United States, causing infections in both humans and animals.
Increased interest from academic, industrial, and government scientists in the pathogenic molds and yeasts has stimulated research that has resulted in a significant expansion of our knowledge of the biology, molecular genetics, clinical expression, diagnosis, and management of fungal diseases.Medical Mycology has, therefore, been thoroughly revised and updated for this edition to include coverage of all newly identified and emerging fungal pathogens or fungal infections, innovative research, and the development of applications of new technology in the field. Medical Mycology provides comprehensive coverage of the pathogenic fungi and the diseases they cause. The volume covers the history, the biologic and molecular taxonomy of the fungal pathogens, diagnostic techniques, and integration of newer antifungal agents and strategies for the management of fungal pathogens, followed by detailed reviews of the etiological agents grouped by the principle sites that they target and the host response they elicit. Medical Mycology is an important resource for all members of the medical mycology community and associated disciplines, including research scientists, clinical laboratory scientists, infectious disease specialists and other clinicians, and epidemiologists. It will also be a powerful resource and inspiration for students interested in studying the relationship between the fungi and their hosts, leading to the diverse infections that they cause.
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