Micro-Scope Diagnostic Suite V14
Tilo Chopin
The electron microscopy suite contains highly advanced secondary electron microscopes (SEM), transmission electron microscope (TEM) and dual beam focused ion beam (FIB/SEM) system to enable ultra-high resolution micro- and nano- structural characterization, compositional and chemical analysis and crystallographic information. Tooling also offers the ability to investigate non-conducting specimens without intrusive preparation and the possibility to introduce water vapor at sufficient pressures to avoid dehydration damage. The toolset is equipped with Energy Dispersive (EDS) and high resolution, highly sensitive Wavelength Dispersive (WDS), Electron Energy Loss (EELS) Spectroscopy for elemental analysis and mapping. One of the SEMs and FIB are equipped with Electron Back Scattered Diffraction (EBSD) systems for crystal orientation measurement and mapping. Two units in this suite are equipped with STEM detector. This suite is supported by extensive tool set for easy, fast and high-quality electron microscopy sample preparation.
From diagnostic devices such as slit lamps, biometers, and perimeters to surgical microscopes, virtual reality simulators, and ergonomically advanced examination units: we work with scientists, physicians, and educational pioneers to develop solutions that address the biggest challenges in global eye health.
The software uses deep convolutional neural networks for discrimination of positive and negative results and pattern recognition. For example, in the evaluation of anti-nuclear antibodies (ANA) on HEp-2 cells, which is one of the most commonly performed analyses in autoimmune diagnostics, nine different patterns, including DFS 70 and AMA, as well as diverse combinations thereof can be identified to get the most accurate result proposal for every patient. The software also generates titer suggestions from the fluorescence intensities of the incubated dilutions. The ANA pattern classification is compliant with the International Consensus on ANA Patterns (ICAP). The classifier can also be used to evaluate anti-neutrophil granulocyte cytoplasmic antibodies on granulocyte substrates, anti-dsDNA antibodies on Crithidiae luciliae, autoantibodies associated with autoimmune liver diseases on tissue substrates and neuronal autoantibodies on recombinant cell substrates. Many more applications are under development to be added to the repertoire.
As recent medical technology is advancing daily, it is vital to develop functional ophthalmic diagnostic instruments to detect and treat ophthalmology diseases in the ophthalmology field.
At TOMEY, each staff is working as a specialist in ophthalmic diagnostic instruments and creating the future of ophthalmology under 4 principles; "Technology", "Communication", "Education" and "Service".
The detection approach used on the chips is adapted from the CRISPR-based diagnostic SHERLOCK, first described in 2017 and developed by team of scientists from the Broad Institute, the McGovern Institute for Brain Research at MIT, the Institute for Medical Engineering & Science at MIT, and the Wyss Institute for Biologically Inspired Engineering at Harvard University.
To use the CARMEN platform, researchers first extract viral RNA from samples and make copies of this genetic material, similar to the preparation process for RT-qPCR diagnostics currently used for suspected COVID-19 cases. The researchers then add a unique fluorescent color dye to each prepared sample and divide the mixture into tiny droplets.
To showcase the platform's multi-diagnostic capabilities, the team developed a strategy for rapidly testing dozens of samples for the 169 human-associated viruses that have more than 10 published genome sequences. The researchers tested this detection panel against 58 patient samples, using multiple chips. They additionally applied CARMEN on patient samples to differentiate between subtypes of influenza A strains and to detect drug-resistance mutations in HIV.
A full Idexx in house blood pathology suite, allowing our team to analyze your pet's internal chemistry in under half an hour. The ease of access is ideal for pre-surgical blood work, allowing us to detect diseases before they show signs, meaning that our anaesthetics can be as safe as possible.
Equipped with an extensive library and diagnostic tools, and run by dedicated, trained volunteers, the plant clinic serves home gardeners with environmentally sound, research-based advice, education, and solutions to common plant problems.
A new diagnostic workflow is available to test the throughput of your ATR accessories. The workflow will walk you through the test to determine if your ATR accessory is working properly. Contact your Thermo Fisher Scientific Service Engineer for further information.
Sometimes, even after performing skin prick and blood tests, an allergist is unable to arrive at a definitive diagnosis. In this case, you may be asked to undergo an oral food challenge (OFC), a highly accurate diagnostic test for food
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