Haveyou tried the Node Find Look At Rotation? This returns angle of rotation between two points. By plugging in just the X & Y into a vector for 2D, you obtain similar results but one less axis.
For those like me who rely on this angle in order to get a result between -180 and 180; for exemple to make an animation go Clockwise or CounterClockwise, you need to subtract the atan of the second vector to the first like so:
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