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Department of Biomedical Engineering Faculty of Engineering | ||
SEMINAR ANNOUNCEMENT | |||
TOPIC |
Novel Thin Film Nitinol Medical Devices for Vascular Repair | ||
SPEAKER |
Youngjae Chun, PhD University of Pittsburgh, USA | ||
HOST |
Dr. Yap Choon Hwai (bie...@nus.edu.sg) | ||
DATE |
Jan 27, 2014 | ||
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TIME |
1.40 pm – 2.20 pm | ||
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VENUE |
EA-06-06, Faculty of Engineering | ||
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ABSTRACT |
Various endovascular devices containing a novel material (e.g., thin film nitinol) were designed and fabricated for treating life-threatening vascular diseases such as aneurysm and peripheral arterial disease; (I) flow-diverting stents for treating brain aneurysms, (II) covered stents for peripheral arterial disease, and (III) endovascular grafts for abdominal aortic aneurysms. Fundamental issues of embedded medical devices were also investigated, which includes; Invitro and in-vivo hemocompatibility and inflammatory studies with super- hydrophilic surface treated thin film nitinol, microfabrication of the hyperelastic thin film nitinol based on Finite Element Modeling, fluid dynamic investigation of devices, in-vivo swine tests, and histopathology. During these studies novel thin film nitinol stents for small vessels have been successfully fabricated and tested in-vivo with swine. In addition, a new chemical surface treatment for thin film nitinol was discovered that inhibits platelet adhesion and thrombus formation when compared to existing implantable endovascular graft materials. This new discovery is especially significant in small vessels (e.g., less than 4mm in diameter) where thrombus formation has represented a major hurdle for vascular devices. The results of these fundamental studies will prove useful information and approaches treating wide range of small vessel diseases. | ||
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BIOGRAPHY
| Professor Youngjae Chun joined the department in 2011 after receiving his Ph.D. in Mechanical Engineering from the University of California, Los Angeles. He received his M.S. in Mechanical Engineering from UCLA with a specialization in MEMS/ Nano- technology. He obtained his B.S. from Inha University (South Korea) in Mechanical and Aerospace Engineering. Dr. Youngjae Chun's primary research interests include artificial biomaterials, bio-hybrid composites, endovascular devices, diagnostic vascular implants, and micro-bio-systems, as well as well as fundamental device-associated biocompatibility and development of experimental methods. | ||
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Yap Choon Hwai, Ph.D.
Assistant Professor
Department of Biomedical Engineering
National University of Singapore
Blk EA-02-04, 9 Engineering Dr 1, Singapore 117576
Tel: (65) 65164257
Fax: (65) 68723069