Obtaining MD for the WHS_SD_rat template

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Austin Hansen

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Aug 5, 2026, 11:42:17 PMAug 5
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Dear Dr. Yeh, I'm working with the WHS_SD_rat template distributed with DSI Studio, and was wondering if there's a way to recover mean diffusivity in addition to the QA and ISO that are provided. Looking at the fib file I don't see mean diffusivity, so I'm guessing the DTI metrics weren't among the saved outputs. Is there data available where I could reconstruct and output mean diffusivity as well? If not, is there another rat dataset that is available you'd recommend for getting QA, ISO, and MD together? Sprague Dawley would be ideal but isn't essential. Thanks so much for your time and support, Austin Hansen

Frank Yeh

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Aug 6, 2026, 12:10:22 PMAug 6
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I will see what I can do with this and get back to this thread.
Frank

On Wed, Aug 5, 2026, 23:42 'Austin Hansen' via DSI Studio <dsi-s...@googlegroups.com> wrote:
Dear Dr. Yeh, I'm working with the WHS_SD_rat template distributed with DSI Studio, and was wondering if there's a way to recover mean diffusivity in addition to the QA and ISO that are provided. Looking at the fib file I don't see mean diffusivity, so I'm guessing the DTI metrics weren't among the saved outputs. Is there data available where I could reconstruct and output mean diffusivity as well? If not, is there another rat dataset that is available you'd recommend for getting QA, ISO, and MD together? Sprague Dawley would be ideal but isn't essential. Thanks so much for your time and support, Austin Hansen

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Austin Hansen

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Aug 31, 2026, 9:33:18 PMAug 31
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Dr. Yeh, 
I just wanted to follow up and see if you had a chance to look at this any? No problem if not, just wanted to check.
Thanks so much for your time and help!
Austin Hansen

Frank Yeh

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Sep 7, 2026, 12:24:13 AMSep 7
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Hi Austin,

Sorry for the delay. The WHS_SD_rat FIB file does not contain MD, and MD cannot be recovered from the saved QA and ISO maps alone. 

There could be rat data available on fiber data hub and could be used here as a replacement to get MD.

Best,
Frank

On Mon, 31 Aug 2026 18:33:18 -0700 (PDT), “‘Austin Hansen’ via DSI Studio” dsi-s...@googlegroups.com wrote:

Dr. Yeh,
I just wanted to follow up and see if you had a chance to look at this any? No problem if not, just wanted to check.
Thanks so much for your time and help!
Austin Hansen

On Thursday, August 6, 2026 at 9:10:22 AM UTC-7 Frank Yeh wrote:

I will see what I can do with this and get back to this thread.
Frank

On Wed, Aug 5, 2026, 23:42 ‘Austin Hansen’ via DSI Studio dsi-s...@googlegroups.com wrote:

Dear Dr. Yeh,
I’m working with the WHS_SD_rat template distributed with DSI Studio, and was wondering if there’s a way to recover mean diffusivity in addition to the QA and ISO that are provided. Looking at the fib file I don’t see mean diffusivity, so I’m guessing the DTI metrics weren’t among the saved outputs. Is there data available where I could reconstruct and output mean diffusivity as well? If not, is there another rat dataset that is available you’d recommend for getting QA, ISO, and MD together? Sprague Dawley would be ideal but isn’t essential.
Thanks so much for your time and support,
Austin Hansen

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