Trouble aggregating FIB files

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Catrin

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Feb 23, 2026, 12:47:58 PM (yesterday) Feb 23
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Hello, I am trying to create a database of FIB files to do correlational tractography and I would appreciate any help.

I have a group of FIB files that were reconstructed in the past couple of years. I recently created a new group of FIB files (whose original DSI was collected the same way and in the same time period) using the same model and corrections. I can't aggregate a file from the old group with a file from the new group, but I can aggregate files from the same group together.

If I start by creating a new database and select one new file and one old file, only one of them is kept (I think the one first in alphanumeric order). But I am able to create a database of all the old files and a database of all the new files. If I open one of those and then try to add one FIB file from the other group, I get the error message: "cannot find qa in <path>" but I know the file contains qa data because I can see it when I open the FIB file.

The old files are .fib.gz and the new files are .fz but I understand those file types should be the same/compatible. I still tried converting an old .fib.gz->.fz and a new .fz->.fib.gz.  (I open it, then save with the other extension) but that doesn't fix the issue. The old .fib.gz files are also ~150-200 MB large while the new .fz files are just 2 MB and their file sizes do not change when I convert them. 

I am doing everything in the GUI. Do you think the file type is the issue and I am just not converting properly or do you think it's something else? Is it possible to see a larger error message/log when adding a file from one group to a database of the other group fails? Let me know if any other info would be helpful. Thank you!

Frank Yeh

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Feb 23, 2026, 2:02:14 PM (yesterday) Feb 23
to c.zh...@gmail.com, DSI Studio
Mixing old and new FIB files is not ideal, as version differences may
create bias.
The best solution is to reprocess the old file into the new .fz files.

Best regards,
Frank
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