DTI and Lesion Probability Mapping analysis in multiple sclerosis patients

[Alberto Benelli]

Hello DSI Studio expert,

I have collected DTI data from patients with multiple sclerosis who have lesions in the white matter.

I would like to know:

1. What is the best method for analyzing the integrity of the cortico-thalamo-cortical loop?

2. How can I see which bundles are affected by the lesions?

Thank you,

Alberto

[Frank Yeh]

1. Use autotrack to map thalamocortical pathways and get tract statistics.

2. Delineate white matter lesions on T2 flair, and use it as ROI to run fiber tracking.

Best regards 

Frank

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[Alberto Benelli]

Thank you for your reply.

How can I run autotrack for the thalamocortical pathways?

For point 2, do you think it is the right approach to see which bundles have been affected by lesion?

Alberto

[Frank Yeh]

1. Please check out tutorial videos at practicum.labsolver.org

2. It depends on your definition of the "right approach"

Best regards 

Frank

[Alberto Benelli]

I want to know the bundle (not how many fibers) names

[Frank Yeh]

I would suggest checking out neuroanatomy books. The tract recognition function map also help as a reference.

Best regards 

Frank