Regarding the issue of constructing connectivity matrix based on DTI
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Fang Songke
Nov 13, 2025, 5:07:50 AMNov 13
to DSI Studio
Dear Dr. Yeh
Sorry to bother you again. I am currently working on constructing a group-level DTI connectivity matrix using the publicly available HCP 1065 dataset in DSI Studio. Since I am relatively new to this pipeline, I would like to confirm whether my workflow is correct.
Attached you will find images outlining the specific steps I followed. I would be very grateful if you could review the materials and point out any errors or issues.
Here is the preliminary description based on the operational steps I followed:
“We performed deterministic tractography using the modified FACT algorithm in DSI Studio, generating 1,000,000 streamlines. Using the same parameters as in prior work ,specifically, angular cutoff of 55◦, step size of 1.0mm, minimum length of 10mm, maximum length of 400 mm, spindensity function smoothing of 0.0, anda QA threshold determined by DWI signal in the CSF. Each of the streamlines generated was screened for its termination location using an automatically generated white matter mask, to eliminate streamlines with premature termination in the white matter(Is this correct?). Entries in the structural connectome A were constructed by counting the number of streamlines connecting every pair of regions i and j in the augmented Schaefer-232 atlas as done previously.”
best
Songke Fang
Sorry to bother you again. I am currently working on constructing a group-level DTI connectivity matrix using the publicly available HCP 1065 dataset in DSI Studio. Since I am relatively new to this pipeline, I would like to confirm whether my workflow is correct.
Attached you will find images outlining the specific steps I followed. I would be very grateful if you could review the materials and point out any errors or issues.
Here is the preliminary description based on the operational steps I followed:
“We performed deterministic tractography using the modified FACT algorithm in DSI Studio, generating 1,000,000 streamlines. Using the same parameters as in prior work ,specifically, angular cutoff of 55◦, step size of 1.0mm, minimum length of 10mm, maximum length of 400 mm, spindensity function smoothing of 0.0, anda QA threshold determined by DWI signal in the CSF. Each of the streamlines generated was screened for its termination location using an automatically generated white matter mask, to eliminate streamlines with premature termination in the white matter(Is this correct?). Entries in the structural connectome A were constructed by counting the number of streamlines connecting every pair of regions i and j in the augmented Schaefer-232 atlas as done previously.”
best
Songke Fang
Frank Yeh
Nov 13, 2025, 3:20:13 PMNov 13
to fangs...@gmail.com, DSI Studio
Looks okay to me.
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