Question about HCP1065 atlas

[Kengo Ito]

Hi Frank,

I am a student of practicum, during practicum on WK2, you mentioned the HCP1065 Group-average template.

I'm interested in the HCP1065 atlas and study the paper: Yeh, F. C. (2021) Population-Based Tract-To-Region Connectome of the Human Brain and Its Hierarchical Topology, preprint DOI: 10.21203/rs.3.rs-1083262/v1

I have a question about this article : 

1.How to calculate the intersection between the voxel-wise mapping of white matter bundles (white matter) and cortical regions (gray matter) ?

2.Does intersection here refer to the overlapping of voxels? But how could white matter overlap with gray matter?

3.If so, Is any voxel-wise threshold used here to get the binary result?

[Frank Yeh]

> 1.How to calculate the intersection between the voxel-wise mapping of white matter bundles (white matter) and cortical regions (gray matter) ?

The tracts are converted to volumes, and then it is a direct
volume-to-volume multiplication.

> 2.Does intersection here refer to the overlapping of voxels? But how could white matter overlap with gray matter?

Yes, tracts can reach gray matter.

> 3.If so, Is any voxel-wise threshold used here to get the binary result?

No. 1 is connected, and 0 is not connected.

>
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