Differential Tractography——choose GQI？ or QSDR

[Candy CC]

Hi Frank,

In DSI-Studio, selecting GQI during [Step T2] typically results in a good fiber tracking outcome, with the neural pathways appearing normal.

However, if QSDR is chosen with the template set to INDI_rhesus at the same step, the resulting neural trajectories may become disorganized (as depicted in the upper figure, Green color appears at the position of the corpus callosum; and the surface looks like the wind blowing through the grass depicted in the below figure)

The reason for choosing QSDR is based on recommendations from the guide website (https://dsi-studio.labsolver.org/doc/gui_t3_dt.html), which suggests that Type 2 is more suitable for my study involving animal subjects (My animal subjects are macaques,)

I appreciate your insights and guidance on this matter.

[Frank Yeh]

I would suggest QSDR and also make sure the b-table is correct using [b-table][check b-table]

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[Candy CC]

What are the reasons for recommending the use of QSDR? Is it because they are animals? For animal data, it is recommended to register each timepoint data to template space?

I tried [check b-table] and flip b,  the results were not good. Sometimes，after clicking [check b-table], the fiber orientations in all three directions are all incorrect.

[Frank Yeh]

What are the reasons for recommending the use of QSDR? Is it because they are animals?

Yes, and the animal structures are more consistent.

 

For animal data, it is recommended to register each timepoint data to template space?

Yes, unless you want to study volume differences.

 

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[边钺岩]

Hello, Frank.

I also found this problem in human patients. 

[Frank Yeh]

It is very common that QSDR gives different tracking results because it deforms the subject space.

You may check out tutorial videos at practicum.labsolver.org for details

Best regards

Frank