I've developed a Python client library to the
drop.io API. The source is up on Google Code:
http://code.google.com/p/dropio-api-python/
Jake has linked to the project from
http://dev.drop.io/api-libraries/ . It is not 100% complete, but the important pieces are in place.
There is also a non-interactive command line interface available. It allows for adding any number of files, links, or notes to a new or existing drop. You can alternatively use stdin instead of a given file by passing a single dash to the -f (--file) option, similar to curl's -T (--upload-file) option. This could allow your process to pipe its stdout to a drop, or both a local file and a drop by first piping to tee and then to my dropio/client.py.
Next steps: add the project to PyPI for easier installing, and add documentation/examples for library and CLI usage on the project's main page. Code reviews, bug reports, and any other feedback are all welcome!