Legal Psychedelics in Colorado: What’s Allowed in 2025

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Sammy Prat

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Dec 26, 2025, 6:13:41 PM (5 days ago) 12/26/25
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Legal Psychedelics in Colorado: What’s Allowed in 2025
https://psychedelicwellnesshub.com/
Colorado is one of the most progressive U.S. states when it comes to psychedelic reform. With the passage of Proposition 122 (Natural Medicine Health Act), adults can legally possess, grow, and use certain natural psychedelics under specific conditions.
Which Psychedelics Are Legal in Colorado?
For adults 21 years and older, Colorado has decriminalized personal use and possession of the following natural psychedelics:
Psilocybin & psilocin (magic mushrooms)
DMT (dimethyltryptamine)
Mescaline (excluding peyote)
These substances are no longer criminal offenses under state law when used responsibly and privately.
Is Psilocybin Legal in Colorado?
Yes, psilocybin mushrooms are legal for personal use in Colorado for adults 21+. Individuals may:
Possess psilocybin
Grow magic mushrooms at home for personal use
Share psilocybin with other adults without payment
However, selling psilocybin remains illegal under state and federal law.
Psilocybin Healing Centers in Colorado
Colorado is also launching licensed psychedelic healing centers, where psilocybin can be used under professional supervision. These centers are regulated by the state and require trained facilitators. Psilocybin used at these locations must stay on-site and cannot be taken home.

What Is Still Illegal?
Despite decriminalization, some restrictions still apply:
Selling psychedelics is illegal
Public consumption is prohibited
Driving under the influence of psychedelics is illegal
Psychedelics remain illegal under U.S. federal law
Home Cultivation Rules
Adults may grow psilocybin mushrooms on private property for personal use only. Cultivation must not exceed allowed limits or be accessible to minors.
Why Colorado Decriminalized Psychedelics
Colorado voters approved Proposition 122 to support:
Mental health treatment options
Trauma and PTSD research
Harm reduction and education
Regulated, supervised psychedelic therapy
Are Psychedelics Legal Everywhere in Colorado?
State law applies statewide, but local governments may impose zoning or operational limits on healing centers. Always check local regulations.
Final Thoughts
Colorado’s psychedelic laws focus on personal freedom, therapeutic access, and public safety, not commercial sales. If you’re interested in psychedelic legality, education, or wellness policy, Colorado is leading the way in responsible



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