Single gene enrichment

[chloe.p....@gmail.com]

Hi, 

One last question. If I wanted to use this package to check for enrichment in individual genes (do any genes have more de novos than would be expected by chance) should I just use the software with every gene in its own gene set (i.e. the number of gene sets tested would = the number of genes in the genome)? I realize that this sacrifices a lot of power due to multiple hypotheses, but potentially candidate genes could be tested by just testing gene sets (consisting of one gene each) of my candidate genes, correct? Is there another way you might suggest testing for enrichment for de novos in individual candidate genes other than making gene sets of one gene each?

Thanks, 

Chloe O'Connell

[Menachem Fromer]

Yes, that's how we describe doing this in example #2 here:

https://psychgen.u.hpc.mssm.edu/dnenrich/example_script.shtml

--
You received this message because you are subscribed to the Google Groups "dnenrich-users" group.
To unsubscribe from this group and stop receiving emails from it, send an email to dnenrich-user...@googlegroups.com.
To post to this group, send email to dnenric...@googlegroups.com.
To view this discussion on the web visit https://groups.google.com/d/msgid/dnenrich-users/af88b97a-590d-4a15-bf24-7c83ee0b6fff%40googlegroups.com.
For more options, visit https://groups.google.com/d/optout.