I have been developing e-commerce in Django as composite apps and using LESS for all of my custom CSS. I have used django-pipeline to compiled, compressed and version-ed before deployment.
Now I am looking for best way to do theming, I tried to put all colors in style.less files, but that doesn't seems to be enough when one consider future updates to project. Here is site link:
http://doorsale-demo.fanaticlab.com/