Managing multiple subdomains best practices

[Muammar Al-Shedivat]

What are the best practices, when you would like to split your website into multiple subdomains.

For instance: admin.example.com, app.example.com and example.com

On which level should one do it? I see here two solutions:

1. On the reverse proxy level, here you need to start for each subdomain a separate web server

2. On the django level. Here one probably would use either django subdomains or django hosts add-ons

As for now, I'm using the second solution, but sometimes I face problems with reversing urls, etc.

What is the best option in your opinion?