It looks like the recommended approach for hosting a standard Django-based website is to disable keep-alive ( http://www.djangobook.com/en/2.0/chapter12.html#turn-off-keep-alive ). Since REST may necessitate sending a whole slew of HTTP requests to read and / or write hierarchical entities, it probably makes sense to leave keep-alive ON for DRF-based sites.Agreed? And is this documented anywhere?