Oh, no! The serial port pins have moved around a lot. The 4.1 is not a drop-in replacement for 3.6 on my robot control board :-(
That board is a 4-layer surface-mount monster with dual-rail buck converters, high-current power switch, various sensor and motor drivers, a two-way video switch (!) and more. Cost a fair bit to develop, so not likely to just re-route and re-spin it.
Than again, the 600 MHz? If I really needed performance, I'd use a Raspberry Pi 4 or a Jetson of some sort (the Xavier Nano is coming out now, too.) Maybe the 3.6 is the epitome of "wire wiggler" microcontrollers, and anything fancier will just be a two-board solution.