Re: [DIYbio] DNA nano-structure targeted to cell membrane

Matt Lawes

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Jul 28, 2013, 5:54:25 PM7/28/13

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Traditional method is to use a lipidic based transfecrion reagent or a viral particle .....

>matt

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-----Original message-----

From: Aayush Aggarwal <aggar...@gmail.com>
To: "diy...@googlegroups.com" <diy...@googlegroups.com>
Sent: Sun, Jul 28, 2013 17:49:30 EDT
Subject: [DIYbio] DNA nano-structure targeted to cell membrane

hello everyone,

I am working on a project for BIOMOD 2013.

Does anybody know how to target DNA nanostructure to cell membrane...

Thanks

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Cathal Garvey (Tablet)

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Jul 29, 2013, 2:57:44 AM7/29/13

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Regardless of structure, all DNA has a highly charged backbone. Not only charged but positively charged, where most membranes are also positively charged.

Consequently, the nonpolar, repellent membrane is an unlikely target for structural DNA..

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Nathan McCorkle

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Jul 30, 2013, 3:27:32 AM7/30/13

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Matt are there viral sequences that can be used straight from a gene
synthesizer or PCR reaction?

> https://groups.google.com/d/msgid/diybio/ff5bde5f-62e8-4d94-b94f-7aff3f2b8ba3%40blur.