DIY Bioreactor and Bioreactor controller

[Jeff Davies]

I've written an Android program with 4 levels of user: Engineer, Recipie Manager, Operator and Viewer, in order to operate a Bioreactor.

I was growing some control code for a Maximite (australian microcontroller), but realised I needed more power,so bought an Arduino Due (ARM).

The status was: GUI basically works. 

I have played with a $3 bluetooth to serial converter for the maximite, and Atlas scientific pH and DO sensors, and bought an arduino motor controller for impeller and relay board for the valves/feed motors for O2, media, etc.

I was thinking of putting this on sourceforge.net as a project - I can do GPL if that's what people want, and then looking for collaborators.

Status is currently GUI works. Charting to do (interface defined). Bluetooth to do. Microcontroller code to do (have a demo of this - it's pretty easy really).

Idea is to store run data on a SD card near the microcontroller.

Anyone interested in collaborating on this project, or know of people working on an equivalent?

Jeff Davies

jeff.davies (at) gammasensors.net

[Bryan Bishop]

On Sat, Feb 1, 2014 at 11:50 AM, Jeff Davies <hipparc...@googlemail.com> wrote:

I was thinking of putting this on sourceforge.net as a project - I can do GPL if that's what people want, and then looking for collaborators.

I would find that useful. Also, there are bunches of guides for releasing source code in general:

https://help.github.com/categories/54/articles

- Bryan
http://heybryan.org/
1 512 203 0507

[Dakota Hamill]

Yes we are more and more interested in controlling fermentation conditions as we start to scale up broth volumes.  Right now it's just a good ol' 1L Erlenmeyer flask sitting at RT with no agitation.  Would be interesting to see how other parameters effect metabolite production but, we can't afford a $5,000 reactor.  I remember there was a thread a year ago or so on a DIY fermentation reactor but I don't think it got very far.  I have basically zero coding skill but could potentially offer access to some analytical equipment to test levels of compounds of interest under varying conditions. 

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[Dear Cham]

Hi guys.

We are actually working on an OpenBioreactor at La Paillasse, Paris with  Bioproduction Phd, Designers, Bioinformatician and all kind of good wills :)
Hardware design is quickly evolving but includes
-The reactor itself,
-T, PH and DO probes
-Magnetic stirrer, 
-Peristaltic pumps controled via arduino.

We are adding a raspy to serialise different bioreactors so you can test different environmental parameters.


Software (mostly pythonic) is intended to give the user a view on the bioreactor and the ability to control some parameters from online.
Our first version include :
-T°, PH and DO mesurements as a graph
-Peristaltic pump control (>analysis and air flow)


We are heading toward adding to software(in this order)
-Webcam viewing
-T° control (ON/OFF)
-Magnetic stirrer control
-T° control (Setpoint and programmed cycle mode)
...

What would u guys like to see next ?

We plan on githubing a first version around the end of this month so those of you who have few hours to spare could join .

[John Griessen]

On 02/04/2014 12:03 PM, Dear Cham wrote:
> We are adding a raspy to serialise different bioreactors so you can test different environmental parameters.
>
>
> Software (mostly pythonic) is intended to give the user a view on the bioreactor and the ability to control some parameters from
> online.
> Our first version include :
> -T°, PH and DO mesurements as a graph
> -Peristaltic pump control (>analysis and air flow)
>
>
> We are heading toward adding to software(in this order)
> -Webcam viewing
> -T° control (ON/OFF)
> -Magnetic stirrer control
> -T° control (Setpoint and programmed cycle mode)

Makes me think of ROS (Robot Operating System) orchestrating, and micropython on the individual reactors.
The webcam could be handled by a micropython controller taking stills if not full video.
I think getting costs down could matter a lot compared to having full video and
high data rates for a machine that historically has very low amounts of data flowing.

But, getting something out there and working is a big deal and congrats on going so fast!

Your Ras Pi can run ROS...

John Griessen

[Nathan McCorkle]

This is a real nice platform for handling complex video with Arduino,
though $75 isn't as cheap as a raspi
model A + camera (which is $40):
Pixy (CMUcam5)
http://charmedlabs.com/default/?page_id=211

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[Ravasz]

Hi,

If you still want options, then biomonstaaar is yet another open source bioreactor under construction. See here: http://biomonstaaar.com/
This one is also arduino based, has heating/cooling, bubbles in gas, and reports all sensor data to a webserver so you can check it from home :)

Well... at least it should do most of that by the end of the month, currently its just a bunch of wires, chips and git repos. It even has some funding for equipment, and the full design is not yet finalized, so if you want to take part, you are welcomed to join.