Better than the approved vaccines...check it out

[Frank]

Since there was some COVID discussion I thought you might like this:

-  nasal spray

- 230x more potent that current vaccines

- effective against all known variants

- single dose

here:

https://pubmed.ncbi.nlm.nih.gov/34082438/

[Jonathan Street]

This is an IgM antibody that can be given as a nasal spray that may have prophylactic and treatment uses if given soon before or after exposure. It's intended use is *very* different to a vaccine and the comparison does not seem especially useful.

The 230-fold potency figure is comparing the IgM antibody against an IgG antibody on which it was based. Clearly this is a useful boost but no comparison was made against a vaccine.

It was tested as a single dose given either 6 hours before or after infection in mice. It is not clear how frequently it would need to be administered in humans to provide continuous protection - but this would not be it's likely use. A single dose would provide only temporary protection. It might have value as a treatment after a COVID diagnosis is made or as a prophylactic if you have been exposed to someone with COVID.

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