RE: [DIYbio] IP free fluorescent protein
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Sebastian Cocioba
Apr 26, 2014, 1:46:53 PM4/26/14
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I'm using a CDS derived from DNA 2.0s proteins. They are in fact IP free. The sequence is only given once you buy the plasmid. They are quite expensive.
Sebastian S. Cocioba
CEO & Founder
New York Botanics, LLC
Plant Biotech R&D
Sebastian S. Cocioba
CEO & Founder
New York Botanics, LLC
Plant Biotech R&D
From: Mega [Andreas Stuermer]
Sent: 4/26/2014 1:44 PM
To: diy...@googlegroups.com
Subject: [DIYbio] IP free fluorescent protein
Does anyone know whether there are IP free fluorescent proteins?
I remember Cathal once mentioned the patent of wild-type GFP just expired.
However, I would need some easy to use and bright *FP. Excitation like common GFP would be nice.
EGFP is still patented.
What about the DNA 2.0 proteins, are their sequences known?
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Dakota Hamill
Apr 26, 2014, 2:24:21 PM4/26/14
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This is what is frustrating about these things. On one hand, if you
work your ass off for years, it's nice to feel like you will get
rewarded for your hard work, and have ownership over whatever product
or IP you created. On the other hand, it seems to hinder people
making progress on their own work unless they pay X amount of $ to
license said technology. I understand you can use anything you want
in R&D, but you can never make a profit off something if you've used
someone else's IP. Or rather, you can, but you might get sued. Of
course, I am generalizing because I don't know all the rules, and
haven't bothered to learn them as it subtracts from time doing
science.
In terms of "patented" proteins or plasmids, at what point would
modifying the sequence slightly make it a new entity?
As in, you find you can add an extra codon which doesn't affect the
desired behavior of the protein of interest, so does that mean it is
no longer covered by the original IP?
Also, I can't imagine a company going after someone for IP
infringement if the payout wouldn't be worth it.
Can someone really patent a DNA sequence, or just the application of
the protein which results from the DNA sequence.
As in, I didn't think the actually gene for Taq was able to be
patented, but plasmids which had the gene and were used in recombinant
production of the Taq protein was what was actually patented. I don't
know..it's a slippery slope I suppose.
> https://groups.google.com/d/msgid/diybio/-7857283912866611394%40unknownmsgid.
work your ass off for years, it's nice to feel like you will get
rewarded for your hard work, and have ownership over whatever product
or IP you created. On the other hand, it seems to hinder people
making progress on their own work unless they pay X amount of $ to
license said technology. I understand you can use anything you want
in R&D, but you can never make a profit off something if you've used
someone else's IP. Or rather, you can, but you might get sued. Of
course, I am generalizing because I don't know all the rules, and
haven't bothered to learn them as it subtracts from time doing
science.
In terms of "patented" proteins or plasmids, at what point would
modifying the sequence slightly make it a new entity?
As in, you find you can add an extra codon which doesn't affect the
desired behavior of the protein of interest, so does that mean it is
no longer covered by the original IP?
Also, I can't imagine a company going after someone for IP
infringement if the payout wouldn't be worth it.
Can someone really patent a DNA sequence, or just the application of
the protein which results from the DNA sequence.
As in, I didn't think the actually gene for Taq was able to be
patented, but plasmids which had the gene and were used in recombinant
production of the Taq protein was what was actually patented. I don't
know..it's a slippery slope I suppose.
Dakota Hamill
Apr 26, 2014, 2:26:46 PM4/26/14
to diy...@googlegroups.com
Ha, I realized I just asked the same question a while ago in the
thread above this one. Oh well
thread above this one. Oh well
Avery louie
Apr 26, 2014, 2:32:33 PM4/26/14
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Iirc in order to get a patent on an improvement on something, there needs to be a technical improvement, not just adding/removing a codon.
To view this discussion on the web visit https://groups.google.com/d/msgid/diybio/CAGdeWmQALuWLHRhqvtET7uNdrAKQLRPu%2BcrMEDA-rPD73R77dg%40mail.gmail.com.
Dakota Hamill
Apr 26, 2014, 2:39:29 PM4/26/14
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The point wouldn't even be to necessarily improve it, it would be to
modify it in such a way that it is no longer similar to the original
patented sequence, enough so that it wouldn't be covered by the IP.
But IP is specifically written to cover large amounts of modifications
so as to specifically avoid that exact thing happening.
In all honestly I'd say if you have an idea just go for it, if someone
goes to sue you that means you're doing something worthwhile enough to
get attention. If it's unique enough, who knows, maybe the people you
piss off might buy it from you. Or at the least you can put on an
application that you were sued by a large corporation for doing some
badass science.
> https://groups.google.com/d/msgid/diybio/CAL4KOmhaXtvdORi5DzqARJXDtpdkthq%2BXz43DWtJQT7S6qhFPQ%40mail.gmail.com.
modify it in such a way that it is no longer similar to the original
patented sequence, enough so that it wouldn't be covered by the IP.
But IP is specifically written to cover large amounts of modifications
so as to specifically avoid that exact thing happening.
In all honestly I'd say if you have an idea just go for it, if someone
goes to sue you that means you're doing something worthwhile enough to
get attention. If it's unique enough, who knows, maybe the people you
piss off might buy it from you. Or at the least you can put on an
application that you were sued by a large corporation for doing some
badass science.
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