Open Source Hardware (Case studies)

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Dakota Hamill

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May 14, 2026, 7:20:18 PM (2 days ago) May 14
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Has anyone come across any case studies of businesses that have adhered to the open source model and shared all the nitty gritty details of creating, manufacturing, pricing, and selling an open source product for a profit? 

I came across an interesting talk a while back 


Which was then followed by someone who wrote a book on the topic 

Open Hardware Basics and Business Alicia Gibb


I know Adafruit and Sparkfun have done pretty well, but it seems like open source fits well with electrical engineering.  Arduino is now closed source?  MakerBot was a big one in the early days to go closed once they took money. 

This open source bioreactor is cool and is the type of product I'd be interested in seeing a case study on.  https://pioreactor.com

More interested in the science-hardware side of things but wondering of any other examples I've not been able to find.  Seems like there's a lot of individual projects but very few "DIYBio" style companies at the size/scale of AdaFruit or Sparkfun. 

I get that transistors are much cheaper and easier to store than enzymes. 

Hans

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May 15, 2026, 7:00:31 PM (17 hours ago) May 15
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Now THIS is what this mostly dead google groups is about. 
My colleague just got the bioreactor, and it's been pretty amazing as a chemostat to study the effects of doubling time. Really great build.

I remember getting all the enzymes from one of the guys that started the OpenBioeconomy lab (think it was called FreeGenes back then?). But as an individual without a -80C, it's really hard to keep shit going... I packed up my DIY lab a long time ago and rejoined academia to scratch that itch.

I think any Opensauce has to have a financial drive behind it. Someone has to be able to make money off it to keep things going. Otherwise they all just... peter out. 

Also, any of you on the DIYbio discord?

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Dakota Hamill

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May 15, 2026, 7:48:24 PM (16 hours ago) May 15
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I thought Keoni Gandal (Spelling) was doing FreeGenes a while back.  I hear you on the other fronts. I bought 2 Pioreactors and gave them away, rest of lab is in a storage unit, headed back to academia.  Startup life teaches you a lot but rarely pays the bills.  

What's the discord server link? 

If anyone ever wants to apply to YCombinator some day and tackle one of their calls for biotech companies, let me know. 




S James Parsons Jr

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May 15, 2026, 10:01:18 PM (14 hours ago) May 15
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opulo LumenPnP

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