A blood test for the early detection of cancer - Biomarkers Apo10 and TKTL1

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Mike Petersen

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Jun 9, 2021, 2:31:12 PMJun 9
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Hello everyone,
for some time now there has been a company in Germany that offers a blood test to identify 20 different types of cancer at a very early stage. The test is based on the testing of macrophage contents. The method is described here:

https://pubmed.ncbi.nlm.nih.gov/31771043/

Have any of you heard of this before? I wonder why this is not more common in oncology and early detection and if there is a catch?

Thank you very much and best regards
Mike


Frank

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Jun 9, 2021, 3:42:07 PMJun 9
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Early stage cancer screening by detecting biomarkers in blood has been around for about 10 years now.  Examples are Cologuard which detects colon cancer. Kaiser Permanente standardized on it in CA a few years ago.  and EarlyCDT for lung cancer called , which I took years ago. There are are multiple companies that make these tests. the tests usually consist of some combination of samples from blood, saliva, stool, breath, urine, etc. Each cancer screen usually measures multiple biomarkers. Seldom is it an all or nothing result. It's more like you get a score for each molecule and then an oeral risk of having the cancer. As we have discovered new biomarkers for specific cancers, these test products have gotten more sensitive and selective as they add additional molecules to the set that constitutes the test for the given cancer. These tests are underutilized. They can detect cancer well before the soonest it can be seen in imaging. 
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Frank

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Jun 9, 2021, 3:44:11 PMJun 9
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That being said, interestingly, no test developed so far can match the sensitivity of a dog's smell. Dogs trained to detect  particular type  of cancer correctly identify persons with cancer more accurately than the best early stage biomarker screens. 


------ Original Message ------
From: "'Mike Petersen' via DIYbio" <diy...@googlegroups.com>
Sent: 6/9/2021 2:31:11 PM
Subject: [DIYbio] A blood test for the early detection of cancer - Biomarkers Apo10 and TKTL1

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