After trying a simulation with 10 repetitions just to test that everything worked, I moved to 100 reps. Then, after the 55 repetition in the firts design (line 458) I received this message:
Error in optimx.check(par, optcfg$ufn, optcfg$ugr, optcfg$uhess, lower, :
Infeasible point, no further tests
I attach the markdown document in the event you want to check, in the following drive:
It is wierd, if I run the chunks one by one the simulation the first simulation works...Maybe is an issue of knittr but the kind of error reported seems much to do with an optimization issue...