The manga can currently be broken down into 11 parts, following the feats of the Straw Hat Pirates: the East Blue Saga, the Arabasta Saga, the Sky Island Saga, the Water 7 Saga, the Thriller Bark Saga, the Summit War Saga, the Fish-Man Island Saga, the Dressrosa Saga, the Whole Cake Island Saga, the Wano Country Saga, and the Final Saga. Each saga is divided into smaller story arcs.
Influenced by Shanks, Luffy starts his journey to become the Pirate King by finding a treasure hidden by the previous Pirate King Gold Roger . At the beginning of his journey, he battles pirate captain Alvida and frees her cabin boy Koby, who wants to become a Marine. Luffy and Koby reach Shells Town, where they meet corrupt Marine captain Axe-Hand Morgan, his son Helmeppo, and the pirate hunter Roronoa Zoro.
Luffy and his first crew member Zoro arrive at Orange Town where they meet a thief named Nami, who hates pirates. The trio makes an unlikely team, fighting to free the town from the rule of Buggy the Clown.
After Nami forms a partnership with the two as their navigator, the crew reaches Syrup Village and searches for a ship to use. There, they encounter a chronic liar named Usopp. When a devious plot is revealed, Usopp's courage is put to the test as the crew prepare for a battle with the Black Cat Pirates.
Usopp joins the crew as a sniper. In search of a cook for their ship, the crew go to a sea restaurant known as the Baratie. However, the restaurant is attacked by the powerful Don Krieg, who has returned from the Grand Line after being attacked by Dracule Mihawk, and wants to use the Baratie as a vessel to go back.
With Sanji from the Baratie joining the crew and Nami stealing the ship, the crew follow her to an island under the control of the fish-man pirate Arlong. Nami reveals that she is a member of the Arlong Pirates and simply helped the crew so she could take their gold later. But why would she follow a man like Arlong?
After Nami officially joins, the crew heads to the last town before the entrance to the Grand Line, Loguetown, the place where Gold Roger was both born and executed. Not only will they have to deal with a powerful Marine captain and his second-in-command who reminds Zoro of his past, but also previous enemies looking for revenge.
Led by the mysterious Mr. 9 and Ms. Wednesday, the crew go to Whisky Peak, where the townspeople immediately start a party to celebrate their arrival. But there is more to this town than there appears...
On their mission to bring Princess Vivi, who was undercover in Baroque Works as Ms. Wednesday, to Arabasta, the crew land at Little Garden, which is actually a huge island that is still stuck in the prehistoric era. However, there are more than dinosaurs on this island, as the crew soon finds out when they encounter two giants that have been locked in combat for over 100 years and four high-ranking Baroque Works members.
The crew, with Kureha's assistant Tony Tony Chopper among them, finally arrive at Arabasta, which is on the verge of civil war. Vivi must reach the rebels and tell them the real cause behind the conflict, but Crocodile, leader of Baroque Works and one of the Seven Warlords of the Sea, will not just stand by and watch. In the end, Baroque Works, marine forces, pirates, the royal guards, and the rebel army clash in a battle that will determine the fate of the country itself.
The crew tearfully leaves Vivi behind and continue on their journey with Ms. All Sunday, aka Nico Robin, joining as an archaeologist. When a ship inexplicably falls from the sky and the Log Pose begins pointing up, they go to the island of Jaya for information on "Sky Island". There, they encounter Bellamy, a pirate who is heralding a "New Age" where pirates do not dream, and a man named Mont Blanc Cricket, a descendant of a the subject of a cautionary tale.
Riding the Knock Up Stream, the crew finds themselves in the "White Sea", an ocean in the sky. The Straw Hats soon discover that there is a war between the Sky People and the natives who originally inhabited a place known as the Upper Yard. They also learn of the cruel God Enel.
The crew returns to the Blue Sea with gold and dials from Skypiea, only to encounter Foxy the Silver Fox, a pirate who challenges them to a "Davy Back Fight", a series of games where the winner takes crewmates from the loser crew. However, even after defeating Foxy, the Straw Hats encounter an enemy whom they have no hope of beating.
In search of a shipwright to join the crew, the Straw Hats land at the thriving metropolis of Water 7. Here, the crew falls apart as two members leave. To make matters worse, the shipwrights are unable to repair the Straw Hats' ship, their money is stolen by thugs, and they are framed for the attempted assassination of Water 7's mayor, who is also president of the Galley-La Company, a shipbuilding company. They try to find the real culprit, but they soon learn that they may have been caught head over heels by the government assassination group CP9.
The Straw Hats, the Franky Family, and the Galley-La Company team up to rescue Nico Robin, save Franky and avenge Iceburg's assassination attempt. To do this, they attack Enies Lobby, a government stronghold where CP9 is based, declaring war on the World Government.
Resting after their ordeals on Enies Lobby, the Straw Hats' world is turned upside-down as familiar faces return with unexpected revelations for the continuation of their journey. In the New World, Shanks makes his move to protect Whitebeard's subordinate Ace from a familiar face with a horrific new power.
The Straw Hats, now including Franky and the members who previously left, continue their adventure out into the Florian Triangle where they come across a strange barrel which upon opening, sets off a flare. This soon turns into a nightmare when a ghost ship directs them to the haunted island of Thriller Bark, where ghosts, zombies and Warlord of the Sea Gecko Moria await them.
Arriving at the Red Line, the crew, now joined by skeleton musician Brook, searches for a way to get to the famed Fish-Man Island. The Straw Hats are soon diverted from their search when a mermaid and a talking starfish appear, and they soon find themselves saving an old enemy from a kidnapping ring. Things take a turn for the worst when the Straw Hats find themselves cornered at every turn with a Warlord of the Sea, a Marine admiral and World Government officials.
Kuma sends each of the Straw Hat Pirates flying from the Sabaody Archipelago to different islands. This arc centers on Luffy, who lands on an island where only women live. Luffy soon discovers that the women on the island are led by Warlord of the Sea Boa Hancock.
Winning over the heart of the beautiful Hancock, Luffy manages to storm the prison of Impel Down, hoping to save his brother Ace from execution before it sparks an ultimate showdown between the Whitebeard Pirates and the World Government.
Unable to rescue Ace before he was transferred, Luffy and his group of Impel Down escapees follow after him to Marineford. With time running out until Ace's execution, the Whitebeard Pirates and the World Government prepare their forces to clash in a battle that could drastically change the era.
The world reels from the death of Whitebeard, causing chaos to ripple all across the Grand Line. Luffy, struggling to cope with Ace's death, remembers he has something just as important to him: his crew. Will the Straw Hat Pirates ever reunite?
After two years, the Straw Hats are finally beginning their undersea journey to Fish-Man Island, and meet Luffy's friend, former Warlord Jinbe. When a local fortuneteller predicts Luffy destroying Fish-Man Island, the Straw Hats are falsely accused as criminals, and to complicate matters further, an alliance between Hody Jones and Vander Decken IX plots to take over the Ryugu Kingdom.
After entering the New World, the Straw Hats are led to Punk Hazard by a distress call. There, they find a samurai in search of his son, run afoul of Smoker's new Marine platoon, and join Trafalgar Law in a plot to take down one of the Four Emperors. As part of this plot, they are tasked with capturing Caesar Clown, the mad scientist who operates on the island and come to learn of his connections to the Underworld and its influential broker, Warlord of the Sea Donquixote Doflamingo.
The Straw Hats, Law, Kin'emon, and Momonosuke head to Dressrosa with a captive Caesar to broker a deal with Doflamingo, destroy his SMILE Factory, and free the samurai's comrade Kanjuro. They soon discover that both Doflamingo and Dressrosa are shrouded with many secrets, and Law's conflict with Doflamingo quickly turns personal. Luffy works to obtain his late brother's Devil Fruit while the other Straw Hats encounter sparks of rebellion among Dressrosa's populace. The alliance's efforts are further complicated as a new Marine admiral named Fujitora arrives to deal with them.
The Straw Hats, Law, and the samurai head to Zou to reunite with the Straw Hats and Momonosuke who had left Dressrosa early. They meet the Mink Tribe natives and discover that Sanji is gone after getting entangled in a plot between his family and the Big Mom Pirates. They also learn how Jack of the Beasts Pirates attacked Zou earlier, and the samurai reveal just how much Kaidou is connected to them and to their home in Wano, leading to the formation of a new alliance. The Straw Hats then split up again to rescue Sanji and go to Wano.
Luffy's group travels to Whole Cake Island to retrieve Sanji from a political marriage between the Vinsmoke Family and the Charlotte Family. They are caught between the families' hidden agendas, and form an alliance with Jinbe, Caesar, and the Fire Tank Pirates to take down Big Mom and save the Vinsmokes.
The news of the Straw Hats exploits at Totto Land are reported to the world as the royalty from around the world gather at Mary Geoise for the Levely. Meanwhile, the Revolutionary Army prepares for their next move, and Big Mom talks to Kaidou about Luffy.
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