DONT connect the radio yet, make the initialization without connecting
Intialize DigiPi with this profile Xiegu X6100 3087 ttyACM1 19200
reboot Digipi, wait until start in TNC mode, turn off TNC mode.
NOW you can connect the radio. All shoud work as expected now.
Just dont start Digipi with radio connected.
73 de YO4CIL, Costin