Gene Symbol in different Genome builds matching with SNP array data

[Tamil Azhagan]

Dears,

          I am working with 500K SNP array analysis in dChip. Upon analysis of the data, I am matching the SNP ID  with the chromosome, position and gene symbol. When I was trying with NCBI 35(hg17) and NCBI 36 (hg18) genome builds, I did find a difference in gene symbol and phsical position between those two. I need  suggestions from you, what are the reasons for this change? and which build should I follow?

I expect your kind suggestions. Please share with me...

--

Tamilazhagan

Graduate student

[Cheng Li]

Tamil,

Can you give specific steps and examples that lead to the difference? e.g. which files or websites you used to go from SNP to gene symbols.

Cheng

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