Combined different GEO data

[ccye...@gmail.com]

Dear sir:

Is it necessary to use "adjust batch effect" to do clustering when
combining different GEO data set? I used all U133 2.0 chips and use
dchip to normalize.

Yen CC

[Cheng Li]

Yen,

No.

See Item 7 (within chip-type standardization) at this link:
http://biosun1.harvard.edu/complab/dchip/combine%20chip.htm#combine_array

Cheng
http://www.ChengLiLab.org/

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