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What is Ozempic?

Ozempic and Wegovy are both brand names for Semaglutide. This is a long-lasting GLP-1 receptor agonist that can be injected subcutaneously once a week.

It has proven to be effective for weight loss in studies with participants both with and without Type 2 Diabetes. Ozempic was originally created to manage Type 2 Diabetes since it aids in reducing blood glucose levels.

However, it resulted in an additional advantage of weight loss, which was subsequently reinforced as individuals without Type 2 Diabetes began requesting Ozempic to assist in shedding pounds.

Remember that only Wegovy in its injectable form is authorized for treating obesity (the oral form is not).

Semaglutide has been demonstrated to lower cardiovascular (CV) risk factors in patients with confirmed CV conditions in certain CV outcome studies.

How Does Ozempic Function for Weight Reduction?

Previously deemed overweight or obese, the treatment is as follows: Ozempic injections at the highest dosage (2.4 mg weekly) assist in attaining optimal weight loss.

However, patients should not immediately begin with the highest dose, as some may not tolerate it and could experience side effects such as nausea or vomiting. For that reason, a slow escalation of the dosage is advised.

The mechanism of Semaglutide (Ozempic and Wegovy) in promoting weight loss is rather intriguing. GLP-1 is a key incretin hormone found in humans. In other words, it boosts insulin secretion, prevents glucagon release, and limits hepatic gluconeogenesis.

Semaglutide leads to slower gastric emptying, decreased appetite, and lower energy consumption, which explains its positive effects on weight reduction. It slows down the speed at which your stomach processes food following a meal (gastric emptying). The more time it requires for gastric emptying, the longer food remains in your stomach, which makes you feel satisfied for a longer duration.

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